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J R Soc Med. 1996 January; 89(1): 49P–50P.
PMCID: PMC1295644

Favourable outcome of scleroderma renal crisis.


Severe hypertension and rapidly progressive acute renal failure is a well recognized complication of scleroderma, often referred to as the renal crisis, and widely thought to cause irreversible deterioration in renal function. With the advent of angiotensin-converting-enzyme inhibitors (ACE-I) the outlook for patients with this condition has dramatically improved. We report here one such patient.

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Selected References

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  • Chapman PJ, Pascoe MD, van Zyl-Smit R. Successful use of captopril in the treatment of "scleroderma renal crisis". Clin Nephrol. 1986 Aug;26(2):106–108. [PubMed]
  • Brown EA, Macgregor GA, Maini RN. Failure of captopril to reverse the renal crisis of scleroderma. Ann Rheum Dis. 1983 Feb;42(1):52–53. [PMC free article] [PubMed]
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