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J R Soc Med. 1991 November; 84(11): 667–668.
PMCID: PMC1295471

Use of an antibacterial powder spray to prevent post prostatectomy urinary infection.

Abstract

To prevent ascending urinary infection in patients following transurethral prostatectomy, we have studied the use of a topical antibacterial agent applied to the groin and external genitalia. A prospective randomized controlled trial was conducted, with 50 patients being treated by daily application of a 2% polynoxylin powder, and 50 patients acting as untreated controls. Patient age and duration of catheterization were similar in the treated and untreated groups. No significant benefit was seen in the treated cohort (P greater than 0.05) in terms of reduction in postoperative urinary infection.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
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  • Daifuku R, Stamm WE. Association of rectal and urethral colonization with urinary tract infection in patients with indwelling catheters. JAMA. 1984 Oct 19;252(15):2028–2030. [PubMed]
  • Williams M, Hole DJ, Murdoch RW, Ogden AC, Hargreave TB. 48-hour cephradine and post-prostatectomy bacteriuria. Br J Urol. 1980 Aug;52(4):311–315. [PubMed]
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  • ALEXANDER JO. Polynoxylin (Anaflex) in dermatology. Br J Dermatol. 1962 Oct;74:364–371. [PubMed]
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  • Blenkharn JI. Biological activity of polynoxylin--an insoluble urea-formaldehyde condensation product. J Clin Hosp Pharm. 1985 Dec;10(4):367–372. [PubMed]
  • Kiely EA, McCormack T, Cafferkey MT, Falkiner FR, Butler MR. Study of appropriate antibiotic therapy in transurethral prostatectomy. Br J Urol. 1989 Jul;64(1):61–65. [PubMed]
  • Jackaman FR, Chisholm GD. Urinary infection and prostatectomy. Br J Urol. 1975 Oct;47(5):545–548. [PubMed]

Articles from Journal of the Royal Society of Medicine are provided here courtesy of Royal Society of Medicine Press