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J R Soc Med. 1995 December; 88(12): 690–691.
PMCID: PMC1295412

Unrecognized hypocalcaemia diagnosed 36 years after thyroidectomy.


Hypoparathyroidism can present many years after thyroidectomy and symptoms may be non-specific. Hypocalcaemia may cause a variety of physical and mental symptoms and the diagnosis is easily overlooked with serious and potentially fatal consequences. Patients with vague symptoms should always be asked about previous thyroid surgery and serum calcium should be measured.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • KRANE SM. Selected features of the clinical course of hypoparathyroidism. JAMA. 1961 Nov 4;178:472–475. [PubMed]
  • Cox RE. Hypoparathyroidism: an unusual cause of seizures. Ann Emerg Med. 1983 May;12(5):314–315. [PubMed]
  • Snowdon JA, Macfie AC, Pearce JB. Hypocalcaemic myopathy with paranoid psychosis. J Neurol Neurosurg Psychiatry. 1976 Jan;39(1):48–52. [PMC free article] [PubMed]
  • Halperin I, Nubiola A, Vendrell J, Vilardell E. Late-onset hypocalcemia appearing years after thyroid surgery. J Endocrinol Invest. 1989 Jun;12(6):419–420. [PubMed]
  • Juan D. Hypocalcemia. Differential diagnosis and mechanisms. Arch Intern Med. 1979 Oct;139(10):1166–1171. [PubMed]
  • Attie JN, Moskowitz GW, Margouleff D, Levy LM. Feasibility of total thyroidectomy in the treatment of thyroid carcinoma: postoperative radioactive iodine evaluation of 140 cases. Am J Surg. 1979 Oct;138(4):555–560. [PubMed]

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