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J R Soc Med. 1995 October; 88(10): 565–569.
PMCID: PMC1295357

The skinache syndrome.


Chronic pain of unknown aetiology, and characterized by cutaneous trigger points, has been coined the skinache syndrome. The treatment of the skinache syndrome was evaluated in 94 patients by two independent methods 2 years after treatment. After one subcutaneous injection of lidocaine 68% of the patients were cured. The pain recurred in 27 patients having suffered for an average of 2 years. Surgical removal of the cutaneous trigger points cured 77% of the latter patients. The odds ratio of success of surgical treatment versus all other treatments combined was 101.3. The skinache syndrome requires a precise clinical investigation. Even when the origin of the pain in tendons, muscle and adipose tissue is excluded, the skinache syndrome remains a common, debilitating disorder. In contrast to fibromyalgia, the skinache syndrome has a simple and effective cure.

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Selected References

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  • Katon WJ. Chest pain, cardiac disease, and panic disorder. J Clin Psychiatry. 1990 May;51 (Suppl):27–53. [PubMed]
  • Ferrell BA, Ferrell BR, Osterweil D. Pain in the nursing home. J Am Geriatr Soc. 1990 Apr;38(4):409–414. [PubMed]
  • Kames LD, Rapkin AJ, Naliboff BD, Afifi S, Ferrer-Brechner T. Effectiveness of an interdisciplinary pain management program for the treatment of chronic pelvic pain. Pain. 1990 Apr;41(1):41–46. [PubMed]
  • Müller W. Die Pannikulose. Z Rheumaforsch. 1973 May-Jun;32(5):169–176. [PubMed]
  • Rice JR. "Fibrositis" syndrome. Med Clin North Am. 1986 Mar;70(2):455–468. [PubMed]
  • Wysenbeek AJ, Mor F, Lurie Y, Weinberger A. Imipramine for the treatment of fibrositis: a therapeutic trial. Ann Rheum Dis. 1985 Nov;44(11):752–753. [PMC free article] [PubMed]
  • Iwane T, Maruyama M, Matsuki M, Ito Y, Shimoji K. Management of intractable pain in adiposis dolorosa with intravenous administration of lidocaine. Anesth Analg. 1976 Mar-Apr;55(2):257–259. [PubMed]
  • Almay BG. Clinical characteristics of patients with idiopathic pain syndromes. Depressive symptomatology and patient pain drawings. Pain. 1987 Jun;29(3):335–346. [PubMed]
  • Levine J. Pain and analgesia: the outlook for more rational treatment. Ann Intern Med. 1984 Feb;100(2):269–276. [PubMed]
  • Loeser JD, Cousins MJ. Contemporary pain management. Med J Aust. 1990 Aug 20;153(4):208–216. [PubMed]
  • Bourne IH. Treatment of painful conditions of the abdominal wall with local injections. Practitioner. 1980 Sep;224(1347):921–925. [PubMed]
  • Petersen P, Kastrup J. Dercum's disease (adiposis dolorosa). Treatment of the severe pain with intravenous lidocaine. Pain. 1987 Jan;28(1):77–80. [PubMed]
  • Gallegos NC, Hobsley M. Recognition and treatment of abdominal wall pain. J R Soc Med. 1989 Jun;82(6):343–344. [PMC free article] [PubMed]
  • Rasmussen JE, Bassøe CF. Semantic analysis of medical records. Methods Inf Med. 1993 Feb;32(1):66–72. [PubMed]
  • McCain GA, Scudds RA. The concept of primary fibromyalgia (fibrositis): clinical value, relation and significance to other chronic musculoskeletal pain syndromes. Pain. 1988 Jun;33(3):273–287. [PubMed]
  • Drewes AM. Primaer fibromyalgi. Nord Med. 1990;105(3):78–81. [PubMed]
  • Keefe FJ, Caldwell DS, Queen K, Gil KM, Martinez S, Crisson JE, Ogden W, Nunley J. Osteoarthritic knee pain: a behavioral analysis. Pain. 1987 Mar;28(3):309–321. [PubMed]
  • Noordenbos W. Some historical aspects. Pain. 1987 May;29(2):141–150. [PubMed]
  • McMahon S, Koltzenburg M. The changing role of primary afferent neurones in pain. Pain. 1990 Dec;43(3):269–272. [PubMed]
  • Ohrbach R, Gale EN. Pressure pain thresholds, clinical assessment, and differential diagnosis: reliability and validity in patients with myogenic pain. Pain. 1989 Nov;39(2):157–169. [PubMed]
  • Waddell G, Bircher M, Finlayson D, Main CJ. Symptoms and signs: physical disease or illness behaviour? Br Med J (Clin Res Ed) 1984 Sep 22;289(6447):739–741. [PMC free article] [PubMed]
  • Melzack R, Stillwell DM, Fox EJ. Trigger points and acupuncture points for pain: correlations and implications. Pain. 1977 Feb;3(1):3–23. [PubMed]
  • Eisman J, Swezey RL. Juxta-articular adiposis dolorosa: what is it? Report of 2 cases. Ann Rheum Dis. 1979 Oct;38(5):479–482. [PMC free article] [PubMed]
  • Ahles TA, Yunus MB, Masi AT. Is chronic pain a variant of depressive disease? The case of primary fibromyalgia syndrome. Pain. 1987 Apr;29(1):105–111. [PubMed]
  • Nilsen JF, Bassøe CF. Contraception in general practice analyzed by a computerized medical record. Scand J Prim Health Care. 1987 Nov;5(4):217–220. [PubMed]
  • Bassøe CF. Automatisk analyse av journaltekst. Tidsskr Nor Laegeforen. 1994 Jun 30;114(17):1974–1976. [PubMed]

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