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J R Soc Med. 1995 September; 88(9): 502–504.
PMCID: PMC1295326

Modern opioids: uses defined by chrono-pharmacology, not receptor selectivity.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • James MK, Feldman PL, Schuster SV, Bilotta JM, Brackeen MF, Leighton HJ. Opioid receptor activity of GI 87084B, a novel ultra-short acting analgesic, in isolated tissues. J Pharmacol Exp Ther. 1991 Nov;259(2):712–718. [PubMed]
  • Feldman PL, James MK, Brackeen MF, Bilotta JM, Schuster SV, Lahey AP, Lutz MW, Johnson MR, Leighton HJ. Design, synthesis, and pharmacological evaluation of ultrashort- to long-acting opioid analgetics. J Med Chem. 1991 Jul;34(7):2202–2208. [PubMed]
  • Glass PS, Hardman D, Kamiyama Y, Quill TJ, Marton G, Donn KH, Grosse CM, Hermann D. Preliminary pharmacokinetics and pharmacodynamics of an ultra-short-acting opioid: remifentanil (GI87084B). Anesth Analg. 1993 Nov;77(5):1031–1040. [PubMed]
  • Egan TD, Lemmens HJ, Fiset P, Hermann DJ, Muir KT, Stanski DR, Shafer SL. The pharmacokinetics of the new short-acting opioid remifentanil (GI87084B) in healthy adult male volunteers. Anesthesiology. 1993 Nov;79(5):881–892. [PubMed]
  • Rosow C. Remifentanil: a unique opioid analgesic. Anesthesiology. 1993 Nov;79(5):875–876. [PubMed]
  • Westmoreland CL, Hoke JF, Sebel PS, Hug CC, Jr, Muir KT. Pharmacokinetics of remifentanil (GI87084B) and its major metabolite (GI90291) in patients undergoing elective inpatient surgery. Anesthesiology. 1993 Nov;79(5):893–903. [PubMed]
  • Jaffe JH, Schuster CR, Smith BB, Blachley PH. Comparison of acetylmethadol and methadone in the treatment of long-term heroin users. A pilot study. JAMA. 1970 Mar 16;211(11):1834–1836. [PubMed]
  • Freedman RR, Czertko G. A comparison of thrice weekly LAAM and daily methadone in employed heroin addicts. Drug Alcohol Depend. 1981 Nov;8(3):215–222. [PubMed]
  • Kaiko RF, Inturrisi CE. Disposition of acetylmethadol in relation to pharmacologic action. Clin Pharmacol Ther. 1975 Jul;18(1):96–103. [PubMed]
  • Levine R, Zaks A, Fink M, Freedman AM. Levomethadyl acetate. Prolonged duration of opioid effects, including cross tolerance to heroin, in man. JAMA. 1973 Oct 15;226(3):316–318. [PubMed]
  • Makower RM, Pennycook AG, Moulton C. Intravenous drug abusers attending an inner city accident and emergency department. Arch Emerg Med. 1992 Mar;9(1):32–39. [PMC free article] [PubMed]

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