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J R Soc Med. 1995 June; 88(6): 353P–354P.
PMCID: PMC1295246

Acrokeratosis paraneoplastica of Bazex in association with a metastatic neuroendocrine tumour.


Bazex syndrome is a rare cutaneous paraneoplastic phenomenon not previously reported in association with neuroendocrine tumours. We describe a patient who responded well to treatment with octreotide.

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Selected References

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  • Bolognia JL, Brewer YP, Cooper DL. Bazex syndrome (acrokeratosis paraneoplastica). An analytic review. Medicine (Baltimore) 1991 Jul;70(4):269–280. [PubMed]
  • Handfield-Jones SE, Matthews CN, Ellis JP, Das KB, McGibbon DH. Acrokeratosis paraneoplastica of Bazex. J R Soc Med. 1992 Sep;85(9):548–550. [PMC free article] [PubMed]
  • Bazex A, Griffiths A. Acrokeratosis paraneoplastica--a new cutaneous marker of malignancy. Br J Dermatol. 1980 Sep;103(3):301–306. [PubMed]
  • Brenner S, Brayer M, Topilsky M. Acrokeratosis paraneoplastica (Basex) in a patient with bronchial carcinoid tumor. J Am Acad Dermatol. 1987 Sep;17(3):517–518. [PubMed]
  • O'Donnell LJ, Farthing MJ. Therapeutic potential of a long acting somatostatin analogue in gastrointestinal diseases. Gut. 1989 Sep;30(9):1165–1172. [PMC free article] [PubMed]
  • Camisa C. Somatostatin and a long-acting analogue, octreotide acetate. Relevance to dermatology. Arch Dermatol. 1989 Mar;125(3):407–412. [PubMed]

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