Search tips
Search criteria 


Logo of jrsocmedLink to Publisher's site
J R Soc Med. 1995 May; 88(5): 296P–297P.
PMCID: PMC1295212

Chronic bullous dermatosis of childhood: relapse after puberty.


Chronic bullous dermatosis of childhood (CBDC) is a distinctive subepidermal blistering disorder that characteristically involves the perioral area, lower trunk, inner thighs and genitalia. Direct immunofluorescence shows a linear band of IgA at the dermoepidermal junction (DEJ). The eruption usually begins before the age of 6 years and is typically described as self-limiting, clearing with a few months or years. Chronic bullous dermatosis of childhood has many clinical and immunopathological similarities with adult linear IgA disease (LAD) and it has been suggested that they represent different manifestations of the same disease. We report a case of CBDC which started at 2 years of age and which has relapsed twice, first at age 6 years and then again, after puberty, at age 17 years.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (608K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Images in this article

Click on the image to see a larger version.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Marsden RA, McKee PH, Bhogal B, Black MM, Kennedy LA. A study of benign chronic bullous dermatosis of childhood and comparison with dermatitis herpetiformis and bullous pemphigoid occurring in childhood. Clin Exp Dermatol. 1980 Jun;5(2):159–176. [PubMed]
  • Burge S, Wojnarowska F, Marsden A. Chronic bullous dermatosis of childhood persisting into adulthood. Pediatr Dermatol. 1988 Nov;5(4):246–249. [PubMed]
  • Wojnarowska F, Marsden RA, Bhogal B, Black MM. Chronic bullous disease of childhood, childhood cicatricial pemphigoid, and linear IgA disease of adults. A comparative study demonstrating clinical and immunopathologic overlap. J Am Acad Dermatol. 1988 Nov;19(5 Pt 1):792–805. [PubMed]
  • Grant PW. Juvenile dermatitis herpetiformis. Trans St Johns Hosp Dermatol Soc. 1968;54(2):128–136. [PubMed]
  • Wojnarowska F, Whitehead P, Leigh IM, Bhogal BS, Black MM. Identification of the target antigen in chronic bullous disease of childhood and linear IgA disease of adults. Br J Dermatol. 1991 Feb;124(2):157–162. [PubMed]

Articles from Journal of the Royal Society of Medicine are provided here courtesy of Royal Society of Medicine Press