PMCCPMCCPMCC

Search tips
Search criteria 

Advanced

 
Logo of jrsocmedLink to Publisher's site
 
J R Soc Med. 1992 March; 85(3): 142–146.
PMCID: PMC1294814

High resolution SPECT, small deep infarcts and diaschisis.

Abstract

Eighteen cases of lacunar infarction are presented. Six of these cases had a purely motor clinical deficit. All the cases were studied by serial high resolution SPECT (single photon emission computerized tomography) using 99Tcm HMPAO. The degree and extent of the changes in cerebral perfusion consistent with diaschisis were noted and these compared with the severity of the clinical deficit at presentation and over time. No significant correlation between diaschisis and the clinical state was found at any stage. The nature, aetiology and importance of diaschisis are discussed and it is suggested that caution should be exercised in attributing clinical features to diaschisis simply because it may be present.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.2M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Images in this article

Click on the image to see a larger version.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Feeney DM, Baron JC. Diaschisis. Stroke. 1986 Sep-Oct;17(5):817–830. [PubMed]
  • KEMPINSKY WH. Experimental study of distant effects of acute focal brain injury; a study of diaschisis. AMA Arch Neurol Psychiatry. 1958 Apr;79(4):376–389. [PubMed]
  • Pappata S, Tran Dinh S, Baron JC, Cambon H, Syrota A. Remote metabolic effects of cerebrovascular lesions: magnetic resonance and positron tomography imaging. Neuroradiology. 1987;29(1):1–6. [PubMed]
  • Kushner M, Alavi A, Reivich M, Dann R, Burke A, Robinson G. Contralateral cerebellar hypometabolism following cerebral insult: a positron emission tomographic study. Ann Neurol. 1984 May;15(5):425–434. [PubMed]
  • Meneghetti G, Vorstrup S, Mickey B, Lindewald H, Lassen NA. Crossed cerebellar diaschisis in ischemic stroke: a study of regional cerebral blood flow by 133Xe inhalation and single photon emission computerized tomography. J Cereb Blood Flow Metab. 1984 Jun;4(2):235–240. [PubMed]
  • Pantano P, Baron JC, Samson Y, Bousser MG, Derouesne C, Comar D. Crossed cerebellar diaschisis. Further studies. Brain. 1986 Aug;109(Pt 4):677–694. [PubMed]
  • Perani D, Di Piero V, Lucignani G, Gilardi MC, Pantano P, Rossetti C, Pozzilli C, Gerundini P, Fazio F, Lenzi GL. Remote effects of subcortical cerebrovascular lesions: a SPECT cerebral perfusion study. J Cereb Blood Flow Metab. 1988 Aug;8(4):560–567. [PubMed]
  • Pozzilli C, Passafiume D, Bastianello S, D'Antona R, Lenzi GL. Remote effects of caudate hemorrhage: a clinical and functional study. Cortex. 1987 Jun;23(2):341–349. [PubMed]
  • Perani D, Vallar G, Cappa S, Messa C, Fazio F. Aphasia and neglect after subcortical stroke. A clinical/cerebral perfusion correlation study. Brain. 1987 Oct;110(Pt 5):1211–1229. [PubMed]
  • Vallar G, Perani D, Cappa SF, Messa C, Lenzi GL, Fazio F. Recovery from aphasia and neglect after subcortical stroke: neuropsychological and cerebral perfusion study. J Neurol Neurosurg Psychiatry. 1988 Oct;51(10):1269–1276. [PMC free article] [PubMed]
  • Baron JC, D'Antona R, Pantano P, Serdaru M, Samson Y, Bousser MG. Effects of thalamic stroke on energy metabolism of the cerebral cortex. A positron tomography study in man. Brain. 1986 Dec;109(Pt 6):1243–1259. [PubMed]
  • Pappata S, Mazoyer B, Tran Dinh S, Cambon H, Levasseur M, Baron JC. Effects of capsular or thalamic stroke on metabolism in the cortex and cerebellum: a positron tomography study. Stroke. 1990 Apr;21(4):519–524. [PubMed]
  • Metter EJ, Hanson WR, Jackson CA, Kempler D, van Lancker D, Mazziotta JC, Phelps ME. Temporoparietal cortex in aphasia. Evidence from positron emission tomography. Arch Neurol. 1990 Nov;47(11):1235–1238. [PubMed]
  • FISHER CM, CURRY HB. PURE MOTOR HEMIPLEGIA OF VASCULAR ORIGIN. Arch Neurol. 1965 Jul;13:30–44. [PubMed]
  • Brott T, Adams HP, Jr, Olinger CP, Marler JR, Barsan WG, Biller J, Spilker J, Holleran R, Eberle R, Hertzberg V, et al. Measurements of acute cerebral infarction: a clinical examination scale. Stroke. 1989 Jul;20(7):864–870. [PubMed]
  • Côté R, Hachinski VC, Shurvell BL, Norris JW, Wolfson C. The Canadian Neurological Scale: a preliminary study in acute stroke. Stroke. 1986 Jul-Aug;17(4):731–737. [PubMed]
  • MAHONEY FI, BARTHEL DW. FUNCTIONAL EVALUATION: THE BARTHEL INDEX. Md State Med J. 1965 Feb;14:61–65. [PubMed]
  • Kiyosawa M, Baron JC, Hamel E, Pappata S, Duverger D, Riche D, Mazoyer B, Naquet R, MacKenzie ET. Time course of effects of unilateral lesions of the nucleus basalis of Meynert on glucose utilization by the cerebral cortex. Positron tomography in baboons. Brain. 1989 Apr;112(Pt 2):435–455. [PubMed]
  • LASSEN NA. Cerebral blood flow and oxygen consumption in man. Physiol Rev. 1959 Apr;39(2):183–238. [PubMed]
  • Ginsberg MD, Castella Y, Dietrich WD, Watson BD, Busto R. Acute thrombotic infarction suppresses metabolic activation of ipsilateral somatosensory cortex: evidence for functional diaschisis. J Cereb Blood Flow Metab. 1989 Jun;9(3):329–341. [PubMed]
  • Rougemont D, Baron JC, Lebrun-Grandie P, Bousser MG, Cabanis E, Laplane D. Débit sanguin cérébral et extraction d'oxygène dans les hémiplégies lacunaires. Etude semi-quantitative par l'oxygène 15 et la tomographie d'émission. Rev Neurol (Paris) 1983;139(4):277–282. [PubMed]
  • Takano T, Kimura K, Nakamura M, Fukunaga R, Kusunoki M, Etani H, Matsumoto M, Yoneda S, Abe H. Effect of small deep hemispheric infarction on the ipsilateral cortical blood flow in man. Stroke. 1985 Jan-Feb;16(1):64–69. [PubMed]
  • Inugami A, Kanno I, Uemura K, Shishido F, Murakami M, Tomura N, Fujita H, Higano S. Linearization correction of 99mTc-labeled hexamethyl-propylene amine oxime (HM-PAO) image in terms of regional CBF distribution: comparison to C15O2 inhalation steady-state method measured by positron emission tomography. J Cereb Blood Flow Metab. 1988 Dec;8(6):S52–S60. [PubMed]
  • Yonekura Y, Nishizawa S, Mukai T, Fujita T, Fukuyama H, Ishikawa M, Kikuchi H, Konishi J, Andersen AR, Lassen NA. SPECT with [99mTc]-d,l-hexamethyl-propylene amine oxime (HM-PAO) compared with regional cerebral blood flow measured by PET: effects of linearization. J Cereb Blood Flow Metab. 1988 Dec;8(6):S82–S89. [PubMed]
  • Cooper RM, Thurlow GA, Rooney BJ. 2-Deoxyglucose uptake and histologic changes in rat thalamus after neocortical ablations. Exp Neurol. 1984 Jan;83(1):134–143. [PubMed]
  • Dauth GW, Gilman S, Frey KA, Penney JB., Jr Basal ganglia glucose utilization after recent precentral ablation in the monkey. Ann Neurol. 1985 May;17(5):431–438. [PubMed]

Articles from Journal of the Royal Society of Medicine are provided here courtesy of Royal Society of Medicine Press