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J R Soc Med. 1993 April; 86(4): 202–204.
PMCID: PMC1293949

Paraneoplastic syndromes in patients with ovarian neoplasia.

Abstract

The prevalence of several paraneoplastic syndromes associated with ovarian cancer was determined from a clinicopathological study of 908 patients with primary ovarian malignancy in the North East Thames Region. The diversity and rarity of these manifestations are great and the explanation for them is difficult. Circumstantial evidence suggests that in some cases an autoimmune phenomenon is the most plausible cause.

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Selected References

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  • Hudson CN. A review of immunological aspects of gynaecological malignancy. Br J Obstet Gynaecol. 1979 Feb;86(2):154–158. [PubMed]
  • Beilby JO, Horne CH, Milne GD, Parkinson C. Alpha-fetoprotein, alpha-1-antitrypsin, and transferrin in gonadal yolk-sac tumours. J Clin Pathol. 1979 May;32(5):455–461. [PMC free article] [PubMed]
  • Bennett RM, Ginsberg MH, Thomsen S. Carcinomatous polyarthritis. The presenting symptom of an ovarian tumor and association with a platelet activating factor. Arthritis Rheum. 1976 Sep-Oct;19(5):953–958. [PubMed]
  • Whitehouse JM. Circulating antibodies in human malignant disease. Br J Cancer Suppl. 1973 Aug;1:170–174. [PubMed]
  • Gerber MA, Koffler D, Cohen CJ. Circulating antibodies in patients with ovarian carcinoma. Gynecol Oncol. 1977 Sep;5(3):228–232. [PubMed]
  • Poulton TA, Crowther ME, Hay FC, Nineham LJ. Immune complexes in ovarian cancer. Lancet. 1978 Jul 8;2(8080):72–73. [PubMed]
  • Hoyt RE, Hamilton JF. Ovarian cancer associated with the nephrotic syndrome. Obstet Gynecol. 1987 Sep;70(3 Pt 2):513–514. [PubMed]
  • Hall DJ, Dyer ML, Parker JC., Jr Ovarian cancer complicated by cerebellar degeneration: a paraneoplastic syndrome. Gynecol Oncol. 1985 Jun;21(2):240–246. [PubMed]
  • Hetzel DJ, Stanhope CR, O'Neill BP, Lennon VA. Gynecologic cancer in patients with subacute cerebellar degeneration predicted by anti-Purkinje cell antibodies and limited in metastatic volume. Mayo Clin Proc. 1990 Dec;65(12):1558–1563. [PubMed]
  • CHAMBERLAIN MJ, WHITTAKER SR. Hashimoto's disease, dermatomyositis, and ovarian carcinoma. Lancet. 1963 Jun 29;1(7296):1398–1399. [PubMed]
  • Adamson AS, Littlewood TJ, Poston GJ, Hows JM, Wolfe JN. Malignancy presenting as peripheral venous gangrene. J R Soc Med. 1988 Oct;81(10):609–610. [PMC free article] [PubMed]
  • HENDERSON PH., Jr Multiple migratory thrombophlebitis associated with ovarian carcinoma. Am J Obstet Gynecol. 1955 Aug;70(2):452–453. [PubMed]
  • Menzies DN. Two Further Cases of Erythrocytosis Secondary to Fibromyomata. Proc R Soc Med. 1965 Apr;58(4):239–239. [PMC free article] [PubMed]
  • Hammond D, Winnick S. Paraneoplastic erythrocytosis and ectopic erythropoietins. Ann N Y Acad Sci. 1974;230:219–227. [PubMed]
  • Medsger TA, Dixon JA, Garwood VF. Palmar fasciitis and polyarthritis associated with ovarian carcinoma. Ann Intern Med. 1982 Apr;96(4):424–431. [PubMed]
  • DINGLEY ER, MARTEN RH. Adenocarcinoma of the ovary presenting as acanthosis nigricans. J Obstet Gynaecol Br Emp. 1957 Dec;64(6):898–900. [PubMed]
  • PARSONS V, RIGBY B. Cushing's syndrome associated with adenocarcinoma of the ovary. Lancet. 1958 Nov 8;2(7054):992–994. [PubMed]
  • Bollen EC, Lamers CB, Jansen JB, Larsson LI, Joosten HJ. Zollinger-Ellison syndrome due to a gastrin-producing ovarian cystadenocarcinoma. Br J Surg. 1981 Nov;68(11):776–777. [PubMed]
  • Allan SG, Lockhart SP, Leonard RC, Smyth JF. Paraneoplastic hypercalcaemia in ovarian carcinoma. Br Med J (Clin Res Ed) 1984 Jun 9;288(6432):1714–1715. [PMC free article] [PubMed]
  • O'Neill RT, Mikuta JJ. Hypoglycemia associated with serous cystadenocarcinoma of the ovary. Obstet Gynecol. 1970 Feb;35(2):287–289. [PubMed]
  • BROWN H, LANE M. CUSHING'S AND MALIGNANT CARCINOID SYNDROMES FROM OVARIAN NEOPLASM. Arch Intern Med. 1965 Apr;115:490–494. [PubMed]
  • Hayakawa T, Kameya A, Mizuno R, Noda A, Kondo T, Hirabayashi N. Hyperamylasemia with papillary serous cystadenocarcinoma of the ovary. Cancer. 1984 Oct 15;54(8):1662–1665. [PubMed]
  • Taraszewski R, Rosman PM, Knight CA, Cloney DJ. Small cell carcinoma of the ovary. Gynecol Oncol. 1991 May;41(2):149–151. [PubMed]
  • Skrabanek P, McPartlin J, Powell D. Tumor hypercalcemia and "ectopic hyperparathyroidism". Medicine (Baltimore) 1980 Jul;59(4):262–282. [PubMed]
  • Boyer M, Friedlander M, Bannatyne P, Atkinson K. Hypercalcemia in association with mucinous adenocarcinoma of the ovary: a case report. Gynecol Oncol. 1989 Dec;35(3):387–390. [PubMed]
  • Josse RG, Wilson DR, Heersche JN, Mills JR, Murray TM. Hypercalcemia with ovarian carcinoma: evidence of a pathogenetic role for prostaglandins. Cancer. 1981 Sep 1;48(5):1233–1241. [PubMed]
  • Kim W, Bockman R, Lemos L, Lewis JL., Jr Hypercalcemia associated with epidermoid carcinoma in ovarian cystic teratoma. Obstet Gynecol. 1981 Jun;57(6 Suppl):81S–85S. [PubMed]
  • Cocconi G, Ceci G, Juvarra G, Minopoli MR, Cocchi T, Fiaccadori F, Lechi A, Boni P. Successful treatment of subacute cerebellar degeneration in ovarian carcinoma with plasmapheresis. A case report. Cancer. 1985 Nov 1;56(9):2318–2320. [PubMed]
  • Levin L, McHardy JE, Poulton TA, Curling OM, Hudson CN. Tumour associated immunity and immunocompetence in ovarian cancer. Br J Obstet Gynaecol. 1976 May;83(5):393–399. [PubMed]
  • Levin L, McHardy JE, Curling OM, Hudson CN. Tumour antigenicity in ovarian cancer. Br J Cancer. 1975 Aug;32(2):152–159. [PMC free article] [PubMed]

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