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J R Soc Med. 1992 January; 85(1): 12–15.
PMCID: PMC1293453

Drug treatments for mastalgia: 17 years experience in the Cardiff Mastalgia Clinic.

Abstract

Mastalgia commonly presents to medical practitioners. The majority of patients can be managed by exclusion of cancer and reassurance. In some the severity of pain affects the quality of life and drug treatment should be considered. Since its inception 324 patients with cyclical mastalgia and 90 with non-cyclical mastalgia have received a therapeutic trial of drug treatment in the Cardiff Mastalgia Clinic. Overall 92% of those with cyclical mastalgia and 64% with non-cyclical mastalgia obtained a clinically useful response to therapy. Danazol was the most effective drug, with bromocriptine and evening primrose oil having equivalent efficacy. Many fewer adverse events were complained of by patients treated with evening primrose oil than danazol or bromocriptine.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
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  • Pye JK, Mansel RE, Hughes LE. Clinical experience of drug treatments for mastalgia. Lancet. 1985 Aug 17;2(8451):373–377. [PubMed]
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Articles from Journal of the Royal Society of Medicine are provided here courtesy of Royal Society of Medicine Press