PMCCPMCCPMCC

Search tips
Search criteria 

Advanced

 
Logo of jrsocmedLink to Publisher's site
 
J R Soc Med. 1991 May; 84(5): 274–276.
PMCID: PMC1293224

Gastric emptying procedures in the self-poisoned patient: are we forcing gastric content beyond the pylorus?

Abstract

A prospective, randomized, single-blind study was carried out to determine whether gastric content is forced into the small bowel when gastric-emptying procedures are employed in self-poisoned patients. They were asked to swallow barium-impregnated polythene pellets, immediately prior to either gastric lavage or ipecacuanha-induced emesis. A second group of patients, who did not require treatment, were used as controls. Sixty patients were recruited to the study. The data show a significant difference in the number of residual pellets in the small bowel of the treated group (n = 40), when compared with the control group (P less than 0.0001). There was no statistical difference in the number of pellets in the small bowel when the treated groups were compared with each other. In addition, the inefficiency of gastric-emptying procedures is highlighted; 58.5% of the total number of pellets ingested were retained in the gastrointestinal tract of the ipecacuanha-treated group, while 51.8% of total pellets ingested were retained in the gastric lavage-treated group.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (644K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Images in this article

Click on the image to see a larger version.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • LOUW A. Treatment of acute barbituric acid poisoning; ten years' experience at the centre for the treatment of poisoning in Copenhagen. Dan Med Bull. 1958 May;5(4):137–143. [PubMed]
  • Vale JA, Meredith TJ, Proudfoot AT. Syrup of ipecacuanha: is it really useful? Br Med J (Clin Res Ed) 1986 Nov 22;293(6558):1321–1322. [PMC free article] [PubMed]
  • Neuvonen PJ, Vartiainen M, Tokola O. Comparison of activated charcoal and ipecac syrup in prevention of drug absorption. Eur J Clin Pharmacol. 1983;24(4):557–562. [PubMed]
  • Boxer L, Anderson FP, Rowe DS. Comparison of ipecac-induced emesis with gastric lavage in the treatment of acute salicylate ingestion. J Pediatr. 1969 May;74(5):800–803. [PubMed]
  • Danel V, Henry JA, Glucksman E. Activated charcoal, emesis, and gastric lavage in aspirin overdose. Br Med J (Clin Res Ed) 1988 May 28;296(6635):1507–1507. [PMC free article] [PubMed]
  • Vasquez TE, Evans DG, Ashburn WL. Efficacy of syrup of ipecac-induced emesis for emptying gastric contents. Clin Nucl Med. 1988 Sep;13(9):638–639. [PubMed]
  • Tandberg D, Murphy LC. The knee-chest position does not improve the efficacy of ipecac-induced emesis. Am J Emerg Med. 1989 May;7(3):267–270. [PubMed]
  • Saetta JP, Quinton DN. Residual gastric content after gastric lavage and ipecacuanha-induced emesis in self-poisoned patients: an endoscopic study. J R Soc Med. 1991 Jan;84(1):35–38. [PMC free article] [PubMed]
  • Curtis RA, Barone J, Giacona N. Efficacy of ipecac and activated charcoal/cathartic. Prevention of salicylate absorption in a simulated overdose. Arch Intern Med. 1984 Jan;144(1):48–52. [PubMed]
  • Cummings JH, Jenkins DJ, Wiggins HS. Measurement of the mean transit time of dietary residue through the human gut. Gut. 1976 Mar;17(3):210–218. [PMC free article] [PubMed]
  • Kulig K, Bar-Or D, Cantrill SV, Rosen P, Rumack BH. Management of acutely poisoned patients without gastric emptying. Ann Emerg Med. 1985 Jun;14(6):562–567. [PubMed]
  • Proudfoot AT. Abandon gastric lavage in the accident and emergency department? Arch Emerg Med. 1984 Jun;1(2):65–71. [PMC free article] [PubMed]
  • Neuvonen PJ, Elonen E. Effect of activated charcoal on absorption and elimination of phenobarbitone, carbamazepine and phenylbutazone in man. Eur J Clin Pharmacol. 1980 Jan;17(1):51–57. [PubMed]
  • Neuvonen PJ, Elfving SM, Elonen E. Reduction of absorption of digoxin, phenytoin and aspirin by activated charcoal in man. Eur J Clin Pharmacol. 1978 May 31;13(3):213–218. [PubMed]

Articles from Journal of the Royal Society of Medicine are provided here courtesy of Royal Society of Medicine Press