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J R Soc Med. 1990 December; 83(12): 773–775.
PMCID: PMC1292951

Gastrointestinal complications of the haemolytic uraemic syndrome.


The haemolytic uraemic syndrome (HUS) is a well recognized cause of acute renal failure in children. Gastrointestinal involvement is common, and may result in rectal bleeding which can be an important presenting symptom. Previous publications have stressed the importance of correct diagnosis to avoid unnecessary surgery. Occasionally serious gastrointestinal complications do occur. We present five children with life-threatening gastrointestinal complications of the HUS and discuss the indications for laparotomy.

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Selected References

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  • GASSER C, GAUTIER E, STECK A, SIEBENMANN RE, OECHSLIN R. Hämolytisch-urämische Syndrome: bilaterale Nierenrindennekrosen bei akuten erworbenen hämolytischen Anämien. Schweiz Med Wochenschr. 1955 Sep 20;85(38-39):905–909. [PubMed]
  • Edmonson MB, Chesney RW. Hemolytic-uremic syndrome confused with acute appendicitis. Arch Surg. 1978 Jun;113(6):754–755. [PubMed]
  • Smith CD, Schuster SR, Gruppe WE, Vawter GF. Hemolytic-uremic syndrome: a diagnostic and therapeutic dilemma for the surgeon. J Pediatr Surg. 1978 Dec;13(6D):597–604. [PubMed]
  • Gianantonio CA, Vitacco M, Mendilaharzu F, Gallo GE, Sojo ET. The hemolytic-uremic syndrome. Nephron. 1973;11(2):174–192. [PubMed]
  • Sawaf H, Sharp MJ, Youn KJ, Jewell PA, Rabbani A. Ischemic colitis and stricture after hemolytic-uremic syndrome. Pediatrics. 1978 Feb;61(2):315–317. [PubMed]

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