PMCCPMCCPMCC

Search tips
Search criteria 

Advanced

 
Logo of jrsocmedLink to Publisher's site
 
J R Soc Med. 1990 September; 83(9): 557–558.
PMCID: PMC1292813

Histological and environmental changes in longstanding ileal conduits.

Abstract

Seventeen patients with urinary diversions present for between 10 and 17 years were examined endoscopically. The region of the anastomosis was successfully biopsied in 13 cases. Biopsy specimens were examined both histologically and cytologically. Urine was aspirated from the conduits under sterile conditions and sent for qualification of bacterial flora. Histology revealed a variable degree of villous atrophy, mucosal metaplasia, crypt hyperplasia and in one case, antral type gland metaplasia. The finding of hyperplasia was corroborated by flow cytometry which demonstrated a high percentage of cells in G2 and metaphase. The majority of cases showed a colonic type of bacterial colonization and mucin histochemistry demonstrated a colonic type of mucin.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (610K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.
 
 

Images in this article

Click on the image to see a larger version.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Leadbetter GW, Jr, Zickerman P, Pierce E. Ureterosigmoidostomy and carcinoma of the colon. J Urol. 1979 Jun;121(6):732–735. [PubMed]
  • Shousha S, Scott J, Polak J. Ileal loop carcinoma after cystectomy for bladder exstrophy. Br Med J. 1978 Aug 5;2(6134):397–398. [PMC free article] [PubMed]
  • Kochevar J. Adenocarcinoid tumor, goblet cell type, arising in a ureteroileal conduit: a case report. J Urol. 1984 May;131(5):957–959. [PubMed]
  • Tomera KM, Unni KK, Utz DC. Adenomatous polyp in ileal conduit. J Urol. 1982 Nov;128(5):1025–1026. [PubMed]
  • MOSTOFI FK. Potentialities of bladder epithelium. J Urol. 1954 Jun;71(6):705–714. [PubMed]
  • Chiarelli SM, Sandei F. Polyps at the site of ureterosigmoidostomy. Tumori. 1984 Apr 30;70(2):209–215. [PubMed]
  • Gonzalez E, Fowler MR, Venable DD. Primary signet ring cell adenocarcinoma of the bladder (linitis plastica of the bladder): report of a case and review of the literature. J Urol. 1982 Nov;128(5):1027–1030. [PubMed]
  • Deane AM, Woodhouse CR, Parkinson MC. Histological changes in ileal conduits. J Urol. 1984 Dec;132(6):1108–1111. [PubMed]
  • Hill MJ, Hudson MJ, Stewart M. The urinary bacterial flora in patients with three types of urinary tract diversion. J Med Microbiol. 1983 May;16(2):221–226. [PubMed]

Articles from Journal of the Royal Society of Medicine are provided here courtesy of Royal Society of Medicine Press