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J R Soc Med. 1990 June; 83(6): 371–372.
PMCID: PMC1292687

Long-term parenteral nutrition: problems with venous access.


Long-term parenteral nutrition requires central venous access, often difficult in patients who have had several central venous catheterizations. Therapy may be complicated by thrombosis and sepsis which may further compromise central access. We report five cases illustrating such difficulties and suggest that these patients be referred early to specialist centres where experienced catheter insertion and management results in a greatly reduced incidence of complications.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Ladefoged K, Jarnum S. Long-term parenteral nutrition. Br Med J. 1978 Jul 22;2(6132):262–266. [PMC free article] [PubMed]
  • Wilmore DW, Dudrick SJ. Safe long-term venous catheterization. Arch Surg. 1969 Feb;98(2):256–258. [PubMed]
  • Messing B, Peitra-Cohen S, Debure A, Beliah M, Bernier JJ. Antibiotic-lock technique: a new approach to optimal therapy for catheter-related sepsis in home-parenteral nutrition patients. JPEN J Parenter Enteral Nutr. 1988 Mar-Apr;12(2):185–189. [PubMed]
  • Mughal M, Irving M. Home parenteral nutrition in the United Kingdom and Ireland. Lancet. 1986 Aug 16;2(8503):383–387. [PubMed]
  • Albertyn LE, Alcock MK. Diagnosis of internal jugular vein thrombosis. Radiology. 1987 Feb;162(2):505–508. [PubMed]
  • Weissleder R, Elizondo G, Stark DD. Sonographic diagnosis of subclavian and internal jugular vein thrombosis. J Ultrasound Med. 1987 Oct;6(10):577–587. [PubMed]
  • Sitzmann JV, Townsend TR, Siler MC, Bartlett JG. Septic and technical complications of central venous catheterization. A prospective study of 200 consecutive patients. Ann Surg. 1985 Dec;202(6):766–770. [PubMed]
  • Mughal MM. Complications of intravenous feeding catheters. Br J Surg. 1989 Jan;76(1):15–21. [PubMed]

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