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J R Soc Med. 1990 June; 83(6): 360–362.
PMCID: PMC1292684

Prolongation of the antiemetic action of P6 acupuncture by acupressure in patients having cancer chemotherapy.

Abstract

Previous work from our department has shown that P6 acupuncture is an effective adjuvant to conventional antiemetic therapy for patients having cytotoxic drugs. However, its efficacy is limited to about 8 h. The current studies show that the application of an elasticized wrist band with a stud placed over the acupuncture point, and pressed regularly every 2 h, will prolong the antiemetic action for 24 h. This proved more effective in hospitalized patients (20/20) than in outpatients (15/20), presumably due to the encouragement given to regularly press the stud. Nausea and vomiting remain problems with cancer chemotherapy despite the use of antiemetics. Following encouraging results with P6 acupuncture (ACP) in postoperative sickness this has been shown to be effective in cancer chemotherapy in 105 patients who, despite the use of conventional antiemetics had been sick following the previous treatment. Electrical stimulation (10 Hz DC) of P6 point for 5 min before administration of the cytotoxic drugs was effective in preventing sickness in 66% and only 6% got no benefit. The ACP was given with the antiemetics which the patients had been receiving. Although there were no side effects with the ACP, the benefit only lasted 6-8 h. This was not important in hospitalized patients where the treatment could be repeated, but was a problem with outpatients. It has been shown that pressure on the P6 point (acupressure) has an antiemetic action. A commercially available elasticized band with a plastic stud (Sea Band) is an effective method of applying pressure to P6 point.(ABSTRACT TRUNCATED AT 250 WORDS)

Full text

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Penta JS, Poster DS, Bruno S, Macdonald JS. Clinical trials with antiemetic agents in cancer patients receiving chemotherapy. J Clin Pharmacol. 1981 Aug-Sep;21(8-9):11S–22S. [PubMed]
  • Gralla RJ, Itri LM, Pisko SE, Squillante AE, Kelsen DP, Braun DW, Jr, Bordin LA, Braun TJ, Young CW. Antiemetic efficacy of high-dose metoclopramide: randomized trials with placebo and prochlorperazine in patients with chemotherapy-induced nausea and vomiting. N Engl J Med. 1981 Oct 15;305(16):905–909. [PubMed]
  • Kris MG, Gralla RJ, Clark RA, Tyson LB, O'Connell JP, Wertheim MS, Kelsen DP. Incidence, course, and severity of delayed nausea and vomiting following the administration of high-dose cisplatin. J Clin Oncol. 1985 Oct;3(10):1379–1384. [PubMed]
  • Laszlo J. Nausea and vomiting as major complications of cancer chemotherapy. Drugs. 1983 Feb;25 (Suppl 1):1–7. [PubMed]
  • Dundee JW, Chestnutt WN, Ghaly RG, Lynas AG. Traditional Chinese acupuncture: a potentially useful antiemetic? Br Med J (Clin Res Ed) 1986 Sep 6;293(6547):583–584. [PMC free article] [PubMed]
  • Dundee JW, Ghaly RG, Fitzpatrick KT, Abram WP, Lynch GA. Acupuncture prophylaxis of cancer chemotherapy-induced sickness. J R Soc Med. 1989 May;82(5):268–271. [PMC free article] [PubMed]
  • Fry EN. Acupressure and postoperative vomiting. Anaesthesia. 1986 Jun;41(6):661–662. [PubMed]
  • Williams CJ, Davies C, Raval M, Middleton J, Luken J, Stone B. Comparison of starting antiemetic treatment 24 hours before or concurrently with cytotoxic chemotherapy. BMJ. 1989 Feb 18;298(6671):430–431. [PMC free article] [PubMed]

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