PMCCPMCCPMCC

Search tips
Search criteria 

Advanced

 
Logo of jrsocmedLink to Publisher's site
 
J R Soc Med. 1989 December; 82(12): 717–720.
PMCID: PMC1292412

Neurological presentations of AIDS--when to test for HIV.

Abstract

Nine of 122 patients dead from AIDS in central London presented with neurological disease, confirmed pathologically in seven. Seven had no other major systemic manifestations. AIDS needs to be considered in the differential diagnosis of meningitis, dementia, diffuse and focal encephalopathies, brainstem syndromes, myelopathy, visual failure and peripheral nerve syndromes. As AIDS becomes more widespread there will be an increasing need for diagnostic HIV testing in many neurological syndromes.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.1M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Gillon R. Testing for HIV without permission. Br Med J (Clin Res Ed) 1987 Mar 28;294(6575):821–823. [PMC free article] [PubMed]
  • Snider WD, Simpson DM, Nielsen S, Gold JW, Metroka CE, Posner JB. Neurological complications of acquired immune deficiency syndrome: analysis of 50 patients. Ann Neurol. 1983 Oct;14(4):403–418. [PubMed]
  • Levy RM, Bredesen DE, Rosenblum ML. Neurological manifestations of the acquired immunodeficiency syndrome (AIDS): experience at UCSF and review of the literature. J Neurosurg. 1985 Apr;62(4):475–495. [PubMed]
  • Jordan BD, Navia BA, Petito C, Cho ES, Price RW. Neurological syndromes complicating AIDS. Front Radiat Ther Oncol. 1985;19:82–87. [PubMed]
  • Guiloff RJ, Fuller GN, Roberts A, Hargreaves M, Gazzard B, Scaravilli F, Harcourt-Webster JN. Nature, incidence and prognosis of neurological involvement in the acquired immunodeficiency syndrome in central London. Postgrad Med J. 1988 Dec;64(758):919–925. [PMC free article] [PubMed]
  • Fuller GN, Guiloff RJ, Scaravilli F, Harcourt-Webster JN. Combined HIV-CMV encephalitis presenting with brainstem signs. J Neurol Neurosurg Psychiatry. 1989 Aug;52(8):975–979. [PMC free article] [PubMed]
  • Scaravilli F, Daniel SE, Harcourt-Webster N, Guiloff RJ. Chronic basal meningitis and vasculitis in acquired immunodeficiency syndrome. A possible role for human immunodeficiency virus. Arch Pathol Lab Med. 1989 Feb;113(2):192–195. [PubMed]
  • Dick JP, Guiloff RJ, Stewart A, Blackstock J, Bielawska C, Paul EA, Marsden CD. Mini-mental state examination in neurological patients. J Neurol Neurosurg Psychiatry. 1984 May;47(5):496–499. [PMC free article] [PubMed]
  • Eidelberg D, Sotrel A, Vogel H, Walker P, Kleefield J, Crumpacker CS., 3rd Progressive polyradiculopathy in acquired immune deficiency syndrome. Neurology. 1986 Jul;36(7):912–916. [PubMed]
  • Cornblath DR, McArthur JC, Kennedy PG, Witte AS, Griffin JW. Inflammatory demyelinating peripheral neuropathies associated with human T-cell lymphotropic virus type III infection. Ann Neurol. 1987 Jan;21(1):32–40. [PubMed]
  • Lipkin WI, Parry G, Kiprov D, Abrams D. Inflammatory neuropathy in homosexual men with lymphadenopathy. Neurology. 1985 Oct;35(10):1479–1483. [PubMed]
  • Dalakas MC, Pezeshkpour GH, Gravell M, Sever JL. Polymyositis associated with AIDS retrovirus. JAMA. 1986 Nov 7;256(17):2381–2383. [PubMed]
  • Kovacs JA, Kovacs AA, Polis M, Wright WC, Gill VJ, Tuazon CU, Gelmann EP, Lane HC, Longfield R, Overturf G, et al. Cryptococcosis in the acquired immunodeficiency syndrome. Ann Intern Med. 1985 Oct;103(4):533–538. [PubMed]
  • Ho DD, Rota TR, Schooley RT, Kaplan JC, Allan JD, Groopman JE, Resnick L, Felsenstein D, Andrews CA, Hirsch MS. Isolation of HTLV-III from cerebrospinal fluid and neural tissues of patients with neurologic syndromes related to the acquired immunodeficiency syndrome. N Engl J Med. 1985 Dec 12;313(24):1493–1497. [PubMed]
  • Navia BA, Petito CK, Gold JW, Cho ES, Jordan BD, Price RW. Cerebral toxoplasmosis complicating the acquired immune deficiency syndrome: clinical and neuropathological findings in 27 patients. Ann Neurol. 1986 Mar;19(3):224–238. [PubMed]
  • Berger JR, Kaszovitz B, Post MJ, Dickinson G. Progressive multifocal leukoencephalopathy associated with human immunodeficiency virus infection. A review of the literature with a report of sixteen cases. Ann Intern Med. 1987 Jul;107(1):78–87. [PubMed]
  • Navia BA, Jordan BD, Price RW. The AIDS dementia complex: I. Clinical features. Ann Neurol. 1986 Jun;19(6):517–524. [PubMed]
  • Anders KH, Guerra WF, Tomiyasu U, Verity MA, Vinters HV. The neuropathology of AIDS. UCLA experience and review. Am J Pathol. 1986 Sep;124(3):537–558. [PubMed]
  • Tucker T, Dix RD, Katzen C, Davis RL, Schmidley JW. Cytomegalovirus and herpes simplex virus ascending myelitis in a patient with acquired immune deficiency syndrome. Ann Neurol. 1985 Jul;18(1):74–79. [PubMed]
  • Grossniklaus HE, Frank KE, Tomsak RL. Cytomegalovirus retinitis and optic neuritis in acquired immune deficiency syndrome. Report of a case. Ophthalmology. 1987 Dec;94(12):1601–1604. [PubMed]
  • Holland GN, Pepose JS, Pettit TH, Gottlieb MS, Yee RD, Foos RY. Acquired immune deficiency syndrome. Ocular manifestations. Ophthalmology. 1983 Aug;90(8):859–873. [PubMed]
  • Holland GN, Sidikaro Y, Kreiger AE, Hardy D, Sakamoto MJ, Frenkel LM, Winston DJ, Gottlieb MS, Bryson YJ, Champlin RE, et al. Treatment of cytomegalovirus retinopathy with ganciclovir. Ophthalmology. 1987 Jul;94(7):815–823. [PubMed]

Articles from Journal of the Royal Society of Medicine are provided here courtesy of Royal Society of Medicine Press