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J R Soc Med. 1988 November; 81(11): 637–639.
PMCID: PMC1291840

Early experience with gamete intrafallopian transfer (GIFT) and direct intraperitoneal insemination (DIPI).

Abstract

We present our early experience with gamete intrafallopian transfer (GIFT) and direct intraperitoneal insemination (DIPI) combined with intrauterine insemination (IUI), two recently described methods of assisting conception in patients with patent fallopian tubes. Sixty-nine patients (93 cycles) were entered into the study. Thirty-three patients (51 cycles) entered the DIPI/IUI programme and 36 patients (42 cycles) entered the GIFT programme. The mean age, duration and aetiology of infertility were similar in both groups. In the GIFT programme 12 pregnancies occurred, which is a 29% pregnancy rate per cycle and a 33% pregnancy rate per patient. In the DIPI/IUI programme only 3 pregnancies occurred, being a 6% pregnancy rate per cycle and a 9% pregnancy rate per patient. With the live birth rate of in vitro fertilization (IVF) being 12% per embryo transfer, we conclude that GIFT is more successful than either DIPI/IUI or IVF in patients with patent fallopian tubes. Further controlled studies are required to assess the future role of DIPI/IUI in clinical practice.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
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  • Asch RH, Ellsworth LR, Balmaceda JP, Wong PC. Pregnancy after translaparoscopic gamete intrafallopian transfer. Lancet. 1984 Nov 3;2(8410):1034–1035. [PubMed]
  • Asch RH, Balmaceda JP, Ellsworth LR, Wong PC. Gamete intra-fallopian transfer (GIFT): a new treatment for infertility. Int J Fertil. 1985;30(1):41–45. [PubMed]
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  • Forrler A, Badoc E, Moreau L, Dellenbach P, Cranz C, Clavert A, Rumpler Y. Direct intraperitoneal insemination: first results confirmed. Lancet. 1986 Dec 20;2(8521-22):1468–1468. [PubMed]
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  • Asch RH, Balmaceda JP, Ellsworth LR, Wong PC. Preliminary experiences with gamete intrafallopian transfer (GIFT). Fertil Steril. 1986 Mar;45(3):366–371. [PubMed]

Articles from Journal of the Royal Society of Medicine are provided here courtesy of Royal Society of Medicine Press