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J R Soc Med. 1988 November; 81(11): 633–636.
PMCID: PMC1291839

Modulating the oxygen tension in tumours by hypothermia and hyperbaric oxygen.

Abstract

Hypothermia is associated with reduced metabolism of tissues and especially reduced oxygen consumption by tumours. If the blood supply to a hypothermic tumour can be maintained then the hypoxic fraction of cells should be reduced and the radiation response increased. This hypothesis has been tested with radiation under hyperbaric oxygen and increased tumour response has been demonstrated.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
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  • Nias AH, Perry P, Photiou A, Reghebi K. Effect of hypothermia on radiosensitization. Int J Radiat Biol Relat Stud Phys Chem Med. 1986 Aug;50(2):241–251. [PubMed]
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