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J R Soc Med. 1988 January; 81(1): 15–18.
PMCID: PMC1291420

Recent respiratory and enteric adenovirus infection in children in the Manchester area.


Seventy-three group B adenoviruses (29 type 3 and 44 type 7) identified in a recent community outbreak were analysed with restriction endonucleases. Considerable genetic heterogeneity was identified, particularly amongst the type 3 isolates, but this genome variation could not be correlated with either clinical or epidemiological findings. Group F adenoviruses were found in 132 (4.1%) of 3202 stool specimens from children with gastroenteritis and, after rotaviruses, they were the most common viruses identified. Unlike rotaviruses, these enteric adenoviruses were endemic throughout the 3-year study period and the greatest proportion of infections (47.6%) were found in babies under 6 months old.

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Selected References

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  • Brown RS, Nogrady MB, Spence L, Wiglesworth FW. An outbreak of adenovirus type 7 infection in children in Montreal. Can Med Assoc J. 1973 Feb 17;108(4):434–439. [PMC free article] [PubMed]
  • Uhnoo I, Wadell G, Svensson L, Johansson ME. Importance of enteric adenoviruses 40 and 41 in acute gastroenteritis in infants and young children. J Clin Microbiol. 1984 Sep;20(3):365–372. [PMC free article] [PubMed]
  • Wadell G. Molecular epidemiology of human adenoviruses. Curr Top Microbiol Immunol. 1984;110:191–220. [PubMed]
  • Bailey AS, Richmond SJ. Genetic heterogeneity of recent isolates of adenovirus types 3, 4, and 7. J Clin Microbiol. 1986 Jul;24(1):30–35. [PMC free article] [PubMed]
  • Wood DJ, Bailey AS. Detection of adenovirus types 40 and 41 in stool specimens by immune electron microscopy. J Med Virol. 1987 Feb;21(2):191–199. [PubMed]
  • Graham FL, Smiley J, Russell WC, Nairn R. Characteristics of a human cell line transformed by DNA from human adenovirus type 5. J Gen Virol. 1977 Jul;36(1):59–74. [PubMed]
  • Wadell G, Hammarskjöld ML, Winberg G, Varsanyi TM, Sundell G. Genetic variability of adenoviruses. Ann N Y Acad Sci. 1980;354:16–42. [PubMed]
  • Kidd AH. Genome variants of adenovirus 41 (subgroup G) from children with diarrhoea in South Africa. J Med Virol. 1984;14(1):49–59. [PubMed]
  • O'Donnell B, Bell E, Payne SB, Mautner V, Desselberger U. Genome analysis of species 3 adenoviruses isolated during summer outbreaks of conjunctivitis and pharyngoconjunctival fever in the Glasgow and London areas in 1981. J Med Virol. 1986 Mar;18(3):213–227. [PubMed]
  • Brandt CD, Kim HW, Rodriguez WJ, Arrobio JO, Jeffries BC, Stallings EP, Lewis C, Miles AJ, Gardner MK, Parrott RH. Adenoviruses and pediatric gastroenteritis. J Infect Dis. 1985 Mar;151(3):437–443. [PubMed]
  • Champsaur H, Questiaux E, Prevot J, Henry-Amar M, Goldszmidt D, Bourjouane M, Bach C. Rotavirus carriage, asymptomatic infection, and disease in the first two years of life. I. Virus shedding. J Infect Dis. 1984 May;149(5):667–674. [PubMed]

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