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J R Soc Med. 1987 April; 80(4): 210–212.
PMCID: PMC1290760

Measurement and prediction of progress in delayed wound healing.

Abstract

Thirty chronic leg ulcers have been studied under controlled conditions until complete healing occurred. Measurement was performed weekly using a computer-linked stereocamera which is capable of measuring skin defects noninvasively with errors of less than 2%. There was a significant difference in healing rate for the first two weeks between clean ulcers entering the trial directly and ulcers admitted first for cleansing before joining the trial. The difference suggests that the weekly healing rate of an ulcer may take up to 2 weeks to respond to a new form of treatment. Absolute ulcer size, change in ulcer size and rate of epithelial migration did not correlate well with time to complete healing, but percentage change in area in the third week was found to be the parameter which gave the earliest close correlation with time to complete healing. Using this parameter, on the data available it was found that time to complete healing could be predicted to within one week for 50% of the ulcers, making this a simple and useful early predictor of treatment efficiency.

Full text

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Marks J, Hughes LE, Harding KG, Campbell H, Ribeiro CD. Prediction of healing time as an aid to the management of open granulating wounds. World J Surg. 1983 Sep;7(5):641–645. [PubMed]
  • Svedman P. Irrigation treatment of leg ulcers. Lancet. 1983 Sep 3;2(8349):532–534. [PubMed]
  • Al-Hassan JM, Thomson M, Criddle RS. Accelerated wound healing by a preparation from skin of the Arabian Gulf catfish. Lancet. 1983 May 7;1(8332):1043–1044. [PubMed]
  • Bulstrode CJ, Goode AW, Scott PJ. Stereophotogrammetry for measuring rates of cutaneous healing: a comparison with conventional techniques. Clin Sci (Lond) 1986 Oct;71(4):437–443. [PubMed]
  • Gowland Hopkins NF, Jamieson CW. Antibiotic concentration in the exudate of venous ulcers: the prediction of ulcer healing rate. Br J Surg. 1983 Sep;70(9):532–534. [PubMed]
  • Myers MB, Cherry G. Zinc and the healing of chronic leg ulcers. Am J Surg. 1970 Jul;120(1):77–81. [PubMed]
  • Myers MB, Rightor M, Cherry G. Relationship between edema and the healing rate of stasis ulcers of the leg. Am J Surg. 1972 Nov;124(5):666–668. [PubMed]

Articles from Journal of the Royal Society of Medicine are provided here courtesy of Royal Society of Medicine Press