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J R Soc Med. 1987 February; 80(2): 94–96.
PMCID: PMC1290679

Clinical trials in cancer research--philosophical and methodological considerations: discussion paper.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Razis DV. Randomized clinical trials in cancer chemotherapy. J R Soc Med. 1979 May;72(5):390–391. [PMC free article] [PubMed]
  • Gehan EA, Freireich EJ. Cancer clinical trials. A rational basis for use of historical controls. Semin Oncol. 1981 Dec;8(4):430–436. [PubMed]
  • Gold J. Cartesian dualism and the current crisis in medicine--a plea for a philosophical approach: discussion paper. J R Soc Med. 1985 Aug;78(8):663–666. [PMC free article] [PubMed]
  • Schafer A. The ethics of the randomized clinical trial. N Engl J Med. 1982 Sep 16;307(12):719–724. [PubMed]
  • Lavori PW, Louis TA, Bailar JC, 3rd, Polansky M. Designs for experiments--parallel comparisons of treatment. N Engl J Med. 1983 Nov 24;309(21):1291–1299. [PubMed]
  • Mathé G. Clinical examination of drugs, a scientific and ethical challenge. Biomedicine. 1973 May;18(3):169–172. [PubMed]
  • Gehan EA. Comparative clinical trials with historical controls: a statistician's view. Biomedicine. 1978 Sep;28(Spec No):13–19. [PubMed]
  • Peto R. Clinical trial methodology. Biomedicine. 1978 Sep;28(Spec No):24–36. [PubMed]
  • Reizenstein P, Delgado M, Gastiaburu J, Lomme L, Ogier C, Pals H, Schellekens J, Whittaker J, Mathé G. Efficacy of and errors in randomized multicenter trials. A review of 230 clinical trials. Biomed Pharmacother. 1983;37(1):14–24. [PubMed]
  • Cassileth BR, Zupkis RV, Sutton-Smith K, March V. Informed consent -- why are its goals imperfectly realized? N Engl J Med. 1980 Apr 17;302(16):896–900. [PubMed]
  • Taylor KM, Margolese RG, Soskolne CL. Physicians' reasons for not entering eligible patients in a randomized clinical trial of surgery for breast cancer. N Engl J Med. 1984 May 24;310(21):1363–1367. [PubMed]
  • Angell M. Patients' preferences in randomized clinical trials. N Engl J Med. 1984 May 24;310(21):1385–1387. [PubMed]

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