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J R Soc Med. 1987 February; 80(2): 74–76.
PMCID: PMC1290673

Hyperthyroidism in elderly patients with atrial fibrillation and normal thyroid hormone measurements.

Abstract

The results of a study to investigate possible underdiagnosis of hyperthyroidism in the elderly are reported. Four out of 24 patients with atrial fibrillation for which there was no obvious cause and who had normal thyroid hormone measurements were found to have subnormal thyrotropin responses to thyrotropin-releasing hormone and abnormal thyroid scans. The implications of this finding are discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
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  • SANDLER G, WILSON GM. The nature and prognosis of heart disease in thyrotoxicosis. A review of 150 patients treated with 131 I. Q J Med. 1959 Jul;28:347–369. [PubMed]
  • Symons C. Thyroid heart disease. Br Heart J. 1979 Mar;41(3):257–262. [PMC free article] [PubMed]
  • Forfar JC, Feek CM, Miller HC, Toft AD. Atrial fibrillation and isolated suppression of the pituitary-thyroid axis: response to specific antithyroid therapy. Int J Cardiol. 1981;1(1):43–48. [PubMed]
  • Staffurth JS, Gibberd MC, Fui SN. Arterial embolism in thyrotoxicosis with atrial fibrillation. Br Med J. 1977 Sep 10;2(6088):688–690. [PMC free article] [PubMed]
  • Emery P, Staffurth JS. Electrical cardioversion for persistent atrial fibrillation after treatment of thyrotoxicosis. Postgrad Med J. 1982 Dec;58(686):746–748. [PMC free article] [PubMed]
  • Rubenstein HA, Butler VP, Jr, Werner SC. Progressive decrease in serum triiodothyronine concentrations with human aging: radioimmunoassay following extraction of serum. J Clin Endocrinol Metab. 1973 Aug;37(2):247–253. [PubMed]
  • Davies AB, Williams I, John R, Hall R, Scanlon MF. Diagnostic value of thyrotrophin releasing hormone tests in elderly patients with atrial fibrillation. Br Med J (Clin Res Ed) 1985 Sep 21;291(6498):773–776. [PMC free article] [PubMed]
  • Caldwell G, Kellett HA, Gow SM, Beckett GJ, Sweeting VM, Seth J, Toft AD. A new strategy for thyroid function testing. Lancet. 1985 May 18;1(8438):1117–1119. [PubMed]

Articles from Journal of the Royal Society of Medicine are provided here courtesy of Royal Society of Medicine Press