PMCCPMCCPMCC

Search tips
Search criteria 

Advanced

 
Logo of jrsocmedLink to Publisher's site
 
J R Soc Med. 1986 July; 79(7): 387–390.
PMCID: PMC1290374

Has the incidence of radiation-induced bowel damage following treatment of uterine carcinoma changed in the last 20 years?

Abstract

Radiation-induced bowel damage occurred in 4.3% of patients treated primarily by irradiation for uterine carcinoma during the period 1962-1982. There has been a progressive rise in the incidence of radiation damage and radiation-induced rectovaginal fistula during this 20-year period. Radiation from intracavitary sources was a contributory factor in 92% of injured cases. The rising incidence of bowel damage in our patients may be due to an increase in the number of patients receiving a high rectal dose from the intracavitary source. There was a significantly (P less than 0.01) higher incidence of radiation injury in cases of cervical carcinoma compared to endometrial carcinoma. This was because cervical carcinoma tended to present at a more advanced stage than endometrial carcinoma and was more frequently treated with combined external and intracavitary irradiation. There was no significant increase in the incidence of complications among patients undergoing hysterectomy.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (713K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • O'Connell D, Howard N, Joslin CA, Ramsey NW, Liversage WE. A new remotely controlled unit for the treatment of uterine carcinoma. Lancet. 1965 Sep 18;2(7412):570–571. [PubMed]
  • Hope-Stone HF, Klevenhagen SC, Mantell BS, Morgan WY, Scholnick SA. Use of the Curietron at The London Hospital. Clin Radiol. 1981 Jan;32(1):17–23. [PubMed]
  • Strockbine MF, Hancock JE, Fletcher GH. Complications in 831 patients with squamous cell carcinoma of the intact uterine cervix treated with 3,000 rads or more whole pelvis irradiation. Am J Roentgenol Radium Ther Nucl Med. 1970 Feb;108(2):293–304. [PubMed]
  • DeCosse JJ, Rhodes RS, Wentz WB, Reagan JW, Dworken HJ, Holden WD. The natural history and management of radiation induced injury of the gastrointestinal tract. Ann Surg. 1969 Sep;170(3):369–384. [PubMed]
  • Swan RW, Fowler WC, Jr, Boronow RC. Surgical management of radiation injury to the small intestine. Surg Gynecol Obstet. 1976 Mar;142(3):325–327. [PubMed]
  • KOTTMEIER HL. COMPLICATIONS FOLLOWING RADIATION THERAPY IN CARCINOMA OF THE CERVIX AND THEIR TREATMENT. Am J Obstet Gynecol. 1964 Apr 1;88:854–866. [PubMed]
  • Villasanta U. Complications of radiotherapy for carcinoma of the uterine cervix. Am J Obstet Gynecol. 1972 Nov 15;114(6):717–726. [PubMed]

Articles from Journal of the Royal Society of Medicine are provided here courtesy of Royal Society of Medicine Press