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J R Soc Med. 1986 June; 79(6): 334–335.
PMCID: PMC1290342

Postoperative gastric aspirations reduced by glycopyrrolate during upper abdominal surgery.


Glycopyrrolate is shown to reduce the incidence of large volumes (more than 40 ml) of postoperative gastric contents, but not the pH, after major abdominal operations and reduce the consequent risk of regurgitation. It should be preferred to atropine during these procedures.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Hester JB, Heath ML. Proceedings: pulmonary acid aspiration syndrome: should prophylaxis be routine? Br J Anaesth. 1975 May;47(5):630–631. [PubMed]
  • Howells TH, Khanam T, Kreel L, Seymour C, Oliver B, Davies JA. Pharmacological emptying of the stomach with metoclopramide. Br Med J. 1971 Jun 5;2(5761):558–560. [PMC free article] [PubMed]
  • Fry EN. Positioning of nasogastric tubes. Br Med J. 1978 Jan 14;1(6105):110–110. [PMC free article] [PubMed]
  • Mirakhur RK, Dundee JW. Glycopyrrolate: pharmacology and clinical use. Anaesthesia. 1983 Dec;38(12):1195–1204. [PubMed]

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