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J R Soc Med. 1985 October; 78(10): 826–829.
PMCID: PMC1289947

Recombinant human gamma-interferon in primary hepatocellular carcinoma.


A phase II trial of recombinant human gamma-interferon in the treatment of unresectable primary hepatocellular carcinoma is reported. The trial was terminated prematurely after recruitment of only 7 patients because of unacceptable toxicity, predominantly renal. There was no evidence of response in any of the 7 patients but some evidence that disease progression was more rapid during the treatment period.

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Selected References

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