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J R Soc Med. 1985 August; 78(8): 638–640.
PMCID: PMC1289836

Familial "hashitoxic' periodic paralysis.


Four members of a Chinese family who had thyrotoxicosis and periodic paralysis are described. Two of these patients had "hashitoxicosis' (Graves' disease and Hashimoto's thyroiditis) as evidenced by the presence of thyroid antibodies in addition to elevated thyroxine (T4) levels. The other two patients were not available for testing. The association of the familial occurrence of "hashitoxicosis' and periodic paralysis does not appear to have been reported previously.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Ali AS, Akavaram NR. Neuromuscular disorders in thyrotoxicosis. Am Fam Physician. 1980 Sep;22(3):97–102. [PubMed]
  • Fisher J. Thyrotoxic periodic paralysis with ventricular fibrillation. Arch Intern Med. 1982 Jul;142(7):1362–1364. [PubMed]
  • Johnson V, Winternitz WW. Hypokalemic periodic paralysis. South Med J. 1984 Sep;77(9):1207–1209. [PubMed]
  • Kusakabe T, Yoshida M, Nishikawa M. Thyrotoxic periodic paralysis: a peculiar case with unusual dystonic behavior and variable relations of paralysis to serum potassium levels. J Clin Endocrinol Metab. 1976 Oct;43(4):730–740. [PubMed]
  • Unreviewed reports. Br Med J (Clin Res Ed) 1984 Aug 4;289(6440):290–290. [PMC free article] [PubMed]
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  • Melnick B, Chang JL, Larson CE, Bedger RC. Hypokalemic familial periodic paralysis. Anesthesiology. 1983 Mar;58(3):263–265. [PubMed]
  • Papouchado M. Thyrotoxic periodic paralysis. J R Soc Med. 1980 Jul;73(7):519–520. [PMC free article] [PubMed]
  • Shah N, Kussman MJ, Tulgan H. Familial periodic paralysis and hyperthyroidism. N Y State J Med. 1979 Oct;79(11):1770–1771. [PubMed]
  • Yeung RT, Tse TF. Thyrotoxic periodic paralysis. Effect of propranolol. Am J Med. 1974 Oct;57(4):584–590. [PubMed]

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