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J R Soc Med. 1985 June; 78(6): 456–458.
PMCID: PMC1289774

Use of alfentanil in short anaesthetic procedures.


The pharmacokinetics of alfentanil, a new and very short-acting opioid, are discussed. Its use in day-case gynaecological procedures is described, and the results of the initial study presented. Alfentanil is a valuable adjunct to anaesthesia for day-case surgery and for short, painful procedures.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Bovill JG, Sebel PS, Blackburn CL, Heykants J. The pharmacokinetics of alfentanil (R39209): a new opioid analgesic. Anesthesiology. 1982 Dec;57(6):439–443. [PubMed]
  • Bower S, Hull CJ. Comparative pharmacokinetics of fentanyl and alfentanil. Br J Anaesth. 1982 Aug;54(8):871–877. [PubMed]
  • Hackett GH, Harris MN, Plantevin OM, Pringle HM, Garrioch DB, Avery AJ. Anaesthesia for outpatient termination of pregnancy. A comparison of two anaesthetic techniques. Br J Anaesth. 1982 Aug;54(8):865–870. [PubMed]
  • Hull CJ, Jacobson L. A clinical trial of alfentanil as an adjuvant for short anaesthetic procedures. Br J Anaesth. 1983;55 (Suppl 2):173S–178S. [PubMed]
  • Hunt TM, Plantevin OM, Gilbert JR. Morbidity in gynaecological day-case surgery. A comparison of two anaesthetic techniques. Br J Anaesth. 1979 Aug;51(8):785–787. [PubMed]
  • Kay B, Stephenson DK. Alfentanyl (R39209): initial clinical experience with a new narcotic analgesic. Anaesthesia. 1980 Dec;35(12):1197–1201. [PubMed]
  • Meuldermans WE, Hurkmans RM, Heykants JJ. Plasma protein binding and distribution of fentanyl, sufentanil, alfentanil and lofentanil in blood. Arch Int Pharmacodyn Ther. 1982 May;257(1):4–19. [PubMed]
  • Stanford BJ, Plantevin OM, Gilbert JR. Morbidity after day-case gynaecological surgery. Comparison of enflurane with halothane. Br J Anaesth. 1979 Dec;51(12):1143–1145. [PubMed]
  • Stanski DR, Hug CC., Jr Alfentanil--a kinetically predictable narcotic analgesic. Anesthesiology. 1982 Dec;57(6):435–438. [PubMed]

Articles from Journal of the Royal Society of Medicine are provided here courtesy of Royal Society of Medicine Press