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Logo of compmedJournal Web siteSee also archive of Canadian Journal of Comparative MedicineNow Published as Canadian Journal of Veterinary ResearchFormerly published as Canadian Journal of Comparative Medicine and Veterinary Science. 1940 to 1968.
Can J Comp Med. 1975 October; 39(4): 416–420.
PMCID: PMC1277489

In vitro antimicrobial sensitivity of Mycoplasmas isolated from the bovine genital tract.


The in vitro antimicrobial sensitivity of 14 mycoplasma and 13 ureaplasma strains isolated from the genital tracts of bulls was examined. It was found that at relatively low concentrations, tetracycline, declomycin and tylosin were lethal to both types of organisms. Lincospectin, berenil, streptomycin and erythromycin were lethal to mycoplasmas but were only inhibitory to the ureaplasma strains at the same concentrations. Polymyxin B and novobiocin were ineffective at the levels tested.

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Selected References

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  • Afshar A, Stuart P, Huck RA. Granular vulvovaginitis (nodular venereal disease) of cattle associated with Mycoplasma bovigenitalium. Vet Rec. 1966 Apr 9;78(15):512–518. [PubMed]
  • al-Aubaidi JM, McEntee K, Lein DH, Roberts SJ. Bovine seminal vesiculitis and epididymitis caused by Mycoplasma bovigenitalium. Cornell Vet. 1972 Oct;62(4):581–586. [PubMed]
  • Davies G. Isolation of mycoplasma from calf lungs. J Comp Pathol. 1967 Oct;77(4):353–357. [PubMed]
  • Gnarpe H, Friberg J. T-mycoplasmas as a possible cause for reproductive failure. Nature. 1973 Mar 9;242(5393):120–121. [PubMed]
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  • Hamdy AH, Miller CC. Antibiotics for bovine mycoplasmas. J Dairy Sci. 1971 Oct;54(10):1541–1544. [PubMed]
  • Kato H, Murakami T, Takase S, Ono K. Sensitivities in vitro to antibiotics of Mycoplasma isolated from canine sources. Nihon Juigaku Zasshi. 1972 Jun;34(4):197–206. [PubMed]
  • Leach RH. Comparative studies of mycoplasma of bovine origin. Ann N Y Acad Sci. 1967 Jul 28;143(1):305–316. [PubMed]
  • Ogata M, Atobe H, Kushida H, Yamamoto K. In vitro sensitivity of mycoplasmas isolated from various animals and sewage to antibiotics and nitrofurans. J Antibiot (Tokyo) 1971 Jul;24(7):443–451. [PubMed]
  • Ruhnke HL. Isolation of an apparently new species of Mycoplasma from cattle. Vet Rec. 1975 Mar 1;96(9):203–203. [PubMed]
  • Stewart SM, Burnet ME, Young JE. In-vitro sensitivity of strains of mycoplasmas from human sources to antibiotics and to sodium aurothiomalate and tylosin tartrate. J Med Microbiol. 1969 Aug;2(3):287–292. [PubMed]

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