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Logo of cjvetresCVMACanadian Journal of Veterinary ResearchSee also Canadian Journal of Comparative MedicineJournal Web siteHow to Submit
 
Can J Vet Res. 1993 January; 57(1): 9–13.
PMCID: PMC1263581

Alterations of fluid and electrolyte balance in thoroughbred racehorses following strenuous exercise during training.

Abstract

Alterations of acid-base status, and fluid and electrolyte balance subsequent to exercise in Thoroughbred racehorses in North America have not been well-characterized. Des-cribed here are the results of an observational study conducted to characterize changes in fluid and electrolytes following strenuous exercise of 16 Thoroughbreds under routine training conditions. Changes following strenuous exercise were determined for the following variables: serum concentrations of sodium (Na), potassium (K), chloride (Cl) and protein; pH of blood; osmolality of plasma and urine; body weight; and, fractional urinary excretion (FE) of Na, K and Cl. The following changes occurred during exercise: increased concentration of Na in blood; increased FE of Na; decreased concentration of Cl in blood; decreased FE of Cl; increased urinary and plasmal osmolality; weight-loss; decreased pH of blood; and, increased concentration of lactic acid. The concurrent decreased concentration of chloride in plasma and acidemia in these horses differed from the hypochloremic, metabolic alkalosis previously described among endurance horses. Acidemia was attributed to production of lactic acid by anaerobic glycolysis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Carlson GP, Mansmann RA. Serum electrolyte and plasma protein alterations in horses used in endurance rides. J Am Vet Med Assoc. 1974 Aug 1;165(3):262–264. [PubMed]
  • Snow DH, Kerr MG, Nimmo MA, Abbott EM. Alterations in blood, sweat, urine and muscle composition during prolonged exercise in the horse. Vet Rec. 1982 Apr 17;110(16):377–384. [PubMed]
  • McKeever KH, Hinchcliff KW, Schmall LM, Muir WW., 3rd Renal tubular function in horses during submaximal exercise. Am J Physiol. 1991 Sep;261(3 Pt 2):R553–R560. [PubMed]
  • Bayly WM, Hodgson DR, Schulz DA, Dempsey JA, Gollnick PD. Exercise-induced hypercapnia in the horse. J Appl Physiol (1985) 1989 Nov;67(5):1958–1966. [PubMed]
  • Rose RJ, Hodgson DR, Kelso TB, McCutcheon LJ, Bayly WM, Gollnick PD. Effects of acetazolamide on metabolic and respiratory responses to exercise at maximal O2 uptake. J Appl Physiol (1985) 1990 Feb;68(2):617–626. [PubMed]
  • Coffman J. Percent creatinine clearance ratios. Vet Med Small Anim Clin. 1980 Apr;75(4):671–676. [PubMed]
  • Rose RJ, Allen JR. Hematologic responses to exercise and training. Vet Clin North Am Equine Pract. 1985 Dec;1(3):461–476. [PubMed]
  • Longhurst JC, Musch TI, Ordway GA. O2 consumption during exercise in dogs--roles of splenic contraction and alpha-adrenergic vasoconstriction. Am J Physiol. 1986 Sep;251(3 Pt 2):H502–H509. [PubMed]
  • Grossman BS, Brobst DF, Kramer JW, Bayly WM, Reed SM. Urinary indices for differentiation of prerenal azotemia and renal azotemia in horses. J Am Vet Med Assoc. 1982 Feb 1;180(3):284–288. [PubMed]

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