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J R Soc Med. 2005 February; 98(2): 83.
PMCID: PMC1079396

Statins and micronutrients: unanswered questions

It is refreshing to read the thoughtful editorial on this subject by Professor McKee and others (October 2004, JRSM1). The interaction of micronutrients, whether administered or in deficiency states, and pharmacotherapy, is a neglected field of study in clinical pharmacology.

The logistical problems posed by studies of this nature are considerable, but suitable and willing volunteers should be relatively easy to recruit. What is necessary is the diversion of some of the energy and resources devoted to new drug assessment to research units dedicated to this sort of basic but vital understanding of the everyday use of drugs and dietary factors, including micronutrients. It may not be too fanciful to say that, from such evidence as there is available, there is scope for reduction in drug usage, with avoidance of some adverse events and alternative solutions to treatment and prevention of certain diseases.


1. McKee M, Moat SJ, McDowell I. Statins and micronutrients: unanswered questions. J R Soc Med 2004;97: 60. [PMC free article] [PubMed]

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