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J Neurol Neurosurg Psychiatry. 1994 February; 57(2): 198–201.
PMCID: PMC1072450

Post-traumatic amnesia: still a valuable yardstick.


Records of coma and post-traumatic amnesia (PTA) were collected for a group of 38 patients with closed head injury. The results confirmed earlier studies indicating that patients may have short or negligible coma but report prolonged PTA. Comparison of eight patients with prolonged PTA (> 7 days) and short coma (< 6 hours) with the rest of the group on MRI in the acute stage showed that these patients had significantly more extensive hemispheric damage. In the group as a whole both coma and PTA were related to the number of areas in central brain structures in which lesions were detected, but only PTA was significantly related to the number of hemispheric areas in which lesions were found. It is concluded that although both coma and PTA are related to brain damage they reflect disparate patterns of lesions. Assessment of PTA can thus provide additional information concerning severity of injury.

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Selected References

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  • Teasdale G, Jennett B. Assessment of coma and impaired consciousness. A practical scale. Lancet. 1974 Jul 13;2(7872):81–84. [PubMed]
  • Alexandre A, Colombo F, Nertempi P, Benedetti A. Cognitive outcome and early indices of severity of head injury. J Neurosurg. 1983 Nov;59(5):751–761. [PubMed]
  • Brooks DN, Aughton ME, Bond MR, Jones P, Rizvi S. Cognitive sequelae in relationship to early indices of severity of brain damage after severe blunt head injury. J Neurol Neurosurg Psychiatry. 1980 Jun;43(6):529–534. [PMC free article] [PubMed]
  • Schacter DL, Crovitz HF. Memory function after closed head injury: a review of the quantitative research. Cortex. 1977 Jun;13(2):150–176. [PubMed]
  • Jordan FM, Cannon A, Murdoch BE. Language abilities of mildly closed head injured (CHI) children 10 years post-injury. Brain Inj. 1992 Jan-Feb;6(1):39–44. [PubMed]
  • Hadley DM, Teasdale GM, Jenkins A, Condon B, MacPherson P, Patterson J, Rowan JO. Magnetic resonance imaging in acute head injury. Clin Radiol. 1988 Mar;39(2):131–139. [PubMed]
  • Levin HS, O'Donnell VM, Grossman RG. The Galveston Orientation and Amnesia Test. A practical scale to assess cognition after head injury. J Nerv Ment Dis. 1979 Nov;167(11):675–684. [PubMed]
  • Shores A, Kraiuhin C, Zurynski Y, Singer A, Gordon E, Marosszeky J, Fearnside MR. Neuropsychological assessment and brain imaging technologies in evaluation of the sequelae of blunt head injury. Aust N Z J Psychiatry. 1990 Mar;24(1):133–138. [PubMed]
  • Annegers JF, Grabow JD, Kurland LT, Laws ER., Jr The incidence, causes, and secular trends of head trauma in Olmsted County, Minnesota, 1935-1974. Neurology. 1980 Sep;30(9):912–919. [PubMed]
  • Ommaya AK, Gennarelli TA. Cerebral concussion and traumatic unconsciousness. Correlation of experimental and clinical observations of blunt head injuries. Brain. 1974 Dec;97(4):633–654. [PubMed]

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