Search tips
Search criteria 


Logo of brjvendisLink to Publisher's site
Br J Vener Dis. 1977 June; 53(3): 173–179.
PMCID: PMC1045385

Neonatal conjunctivitis caused by Neisseria gonorrhoeae and Chlamydia trachomatis.


In a selected group of 103 babies referred with neonatal conjunctivitis Neisseria gonorrhoeae was isolated from 11 and Chlamydia trachomatis from 33. Concurrent infection was present in three. On toddler sibling developed chlamydial conjunctivitis. After treatment C. trachomatis was re-isolated from six babies during the follow-up period. The discharge started one to three days after delivery in only three babies with gonococcal conjunctivitis and at five to eight days in eight babies. One baby was delivered by caesarean section. N. gonorrhoeae was isolated from four asymptomatic fathers, all of whom had urethritis. The mean onset of discharge in the 33 babies from whom Chlamydia was isolated was 7-1 days. One baby was delivered by caesarean section. Chlamydial conjunctivitis was associated with a high incidence of prematurity and of postpartum infection in the mother. Ten fathers of Chlamydia-positive babies were examined. C. tachomatis was isolated from four, all of whom were asymptomatic but had low-grade urethritis. These findings confirm the pathogenic role of C. trachomatis in the cervix and indicate the importance to the family of an adequate microbiological investigation of neonatal conjunctivitis.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.6M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Images in this article

Click on the image to see a larger version.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Dunlop EM, al-Hussaini MK, Freedman A, Garland JA, Harper IA, Jones BR, Race JW, Du Toit MS, Treharne JD, Wright DJ. Infection by TRIC agent and other members of the Bedsonia group; with a note on Reiter's disease. 3. Genital infection and disease of the eye. Trans Ophthalmol Soc U K. 1966;86:321–334. [PubMed]
  • Dunlop EM, Vaughan-Jackson JD, Darougar S, Jones BR. Chlamydial infection. Incidence in 'non-specific' urethritis. Br J Vener Dis. 1972 Dec;48(6):425–428. [PMC free article] [PubMed]
  • Freedman A, al-Hussaini MK, Dunlop MC, Emarah MH, Garland JA, Harper IA, Jones BR, Race JW, Du Toit MS, Treharne JD, et al. Infection by TRIC agent and other members of the Bedsonia group; with a note on Reiter's disease. II. Ophthalmia neonatorum due to TRIC agent. Trans Ophthalmol Soc U K. 1966;86:313–320. [PubMed]
  • Hilton AL, Richmond SJ, Milne JD, Hindley F, Clarke SK. Chlamydia A in the female genital tract. Br J Vener Dis. 1974 Feb;50(1):1–10. [PMC free article] [PubMed]
  • Hobson D, Johnson FW, Rees E, Tait IA. Simplified method for diagnosis of genital and ocular infections with Chlamydia. Lancet. 1974 Sep 7;2(7880):555–556. [PubMed]
  • Holmes KK, Handsfield HH, Wang SP, Wentworth BB, Turck M, Anderson JB, Alexander ER. Etiology of nongonococcal urethritis. N Engl J Med. 1975 Jun 5;292(23):1199–1205. [PubMed]
  • Johnson FW. A comparison of staining techniques for demonstrating group A chlamydia in tissue culture. Med Lab Technol. 1975 Jul;32(3):233–238. [PubMed]
  • Johnson FW, Hobson D. Factors affecting the sensitivity of replicating McCoy cells in the isolation and growth of chlamydia A (TRIC agents). J Hyg (Lond) 1976 Jun;76(3):441–451. [PMC free article] [PubMed]
  • Jones BR. The prevention of blindness from trachoma. Trans Ophthalmol Soc U K. 1975 Apr;95(1):16–33. [PubMed]
  • JONES BR, COLLIER LH, SMITH CH. Isolation of virus from inclusion blennorrhoea. Lancet. 1959 May 2;1(7079):902–905. [PubMed]
  • Mordhorst CH, Dawson C. Sequelae of neonatal inclusion conjunctivitis and associated disease in parents. Am J Ophthalmol. 1971 Apr;71(4):861–867. [PubMed]
  • Oriel JD, Reeve P, Wright JT, Owen J. Chlamydial infection of the male urethra. Br J Vener Dis. 1976 Feb;52(1):46–51. [PMC free article] [PubMed]
  • Percival A, Rowlands J, Corkill JE, Alergant CD, Arya OP, Rees E, Annels EH. Penicillinase-producing Gonococci in Liverpool. Lancet. 1976 Dec 25;2(8000):1379–1382. [PubMed]
  • Watson PG, Gairdner D. TRIC agent as a cause of neonatal eye sepsis. Br Med J. 1968 Aug 31;3(5617):527–528. [PMC free article] [PubMed]
  • Weström L. Effect of acute pelvic inflammatory disease on fertility. Am J Obstet Gynecol. 1975 Mar 1;121(5):707–713. [PubMed]

Articles from The British Journal of Venereal Diseases are provided here courtesy of BMJ Group