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Br J Ophthalmol. 1985 March; 69(3): 205–211.
PMCID: PMC1040564

Pupillary constriction to darkness.


Patients with congenital achromatopsia and congenital stationary night blindness have been known to show a transient pupillary constriction to darkness. We examined 50 normal subjects and 108 patients with retinal and optic nerve dysfunction to see if any had an initial pupillary constriction to darkness. We used a new infrared television apparatus. Four patients with congenital stationary night blindness, four with achromatopsia, two with bilateral optic neuritis, and one with dominant optic atrophy showed the phenomenon. In the patients who showed this unusual pupillary response to darkness it was the first observable event every time the lights were turned off. The constriction could usually be seen with a handlight, and it was similar in latency to the normal pupillary dilatation to darkness. Pupillary constriction to darkness is a clinically valuable sign that can be used in the detection of congenital retinal disease in children with poor vision.

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Selected References

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  • Barricks ME, Flynn JT, Kushner BJ. Paradoxical pupillary responses in congenital stationary night blindness. Arch Ophthalmol. 1977 Oct;95(10):1800–1804. [PubMed]
  • Flynn JT, Kazarian E, Barricks M. Paradoxical pupil in congenital achromatopsia. Int Ophthalmol. 1981 Mar;3(2):91–96. [PubMed]
  • Carr RE. Congenital stationary nightblindness. Trans Am Ophthalmol Soc. 1974;72:448–487. [PMC free article] [PubMed]
  • SCHUBERT G, BORNSCHEIN H. Beitrag zur Analyse des menschlichen Elektroretinogramms. Ophthalmologica. 1952 Jun;123(6):396–413. [PubMed]
  • RIGGS LA. Electroretinography in cases of night blindness. Am J Ophthalmol. 1954 Jul;38(12):70–78. [PubMed]
  • Balkema GW, Mangini NJ, Pinto LH. Discrete visual defects in pearl mutant mice. Science. 1983 Mar 4;219(4588):1085–1087. [PubMed]
  • O'Connor PS, Tredici TJ, Ivan DJ, Mumma JV, Shacklett DE. Achromatopsia. Clinical diagnosis and treatment. J Clin Neuroophthalmol. 1982 Dec;2(4):219–226. [PubMed]
  • Alpern M, Holland MG, Oba N. Rhodopsin bleaching signals in essential night blindness. J Physiol. 1972 Sep;225(2):457–476. [PubMed]

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