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Br J Ophthalmol. 1984 December; 68(12): 901–903.
PMCID: PMC1040506

Granulomatous conjunctivitis in a patient with Crohn's disease.


A 13-year-old boy with severe, active granulomatous ileocolitis presented with bilateral conjunctival nodules and infiltrates, iritis, and uniocular corneal infiltrates. Gastrointestinal biopsy revealed deep focal ulcers of the bowel wall with adjacent granulomas. Conjunctival biopsy disclosed non-caseating granulomatous inflammation.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Greenstein AJ, Janowitz HD, Sachar DB. The extra-intestinal complications of Crohn's disease and ulcerative colitis: a study of 700 patients. Medicine (Baltimore) 1976 Sep;55(5):401–412. [PubMed]
  • Hopkins DJ, Horan E, Burton IL, Clamp SE, de Dombal FT, Goligher JC. Ocular disorders in a series of 332 patients with Crohn's disease. Br J Ophthalmol. 1974 Aug;58(8):732–737. [PMC free article] [PubMed]
  • Reynolds MD, Rankin TJ. Diagnosis of "rheumatoid variants" ankylosing spondylitis, the arthritides of gastrointestinal diseases and psoriasis, and Reiter's syndrome. West J Med. 1974 Jun;120(6):441–447. [PMC free article] [PubMed]
  • Knox DL, Snip RC, Stark WJ. The keratopathy of Crohn's disease. Am J Ophthalmol. 1980 Dec;90(6):862–865. [PubMed]
  • Nugent FW, Glaser D, Fernandez-Herlihy L. Crohn's colitis associated with granulomatous bone disease. N Engl J Med. 1976 Jan 29;294(5):262–263. [PubMed]
  • Frayha R, Stevens MB, Bayless TM. Destructive monarthritis and granulomatous synovitis as the presenting manifestations of Crohn's disease. Johns Hopkins Med J. 1975 Oct;137(4):151–155. [PubMed]

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