PMCCPMCCPMCC

Search tips
Search criteria 

Advanced

 
Logo of brjopthalBritish Journal of OphthalmologyVisit this articleSubmit a manuscriptReceive email alertsContact usBMJ
 
Br J Ophthalmol. 1983 July; 67(7): 443–448.
PMCID: PMC1040092

Relationship between the amplitudes of the b wave and the a wave as a useful index for evaluating the electroretinogram.

Abstract

The present methods for the assessment of the electroretinogram (ERG) make the exchange of data between laboratories difficult owing to differences in photostimulation and recording techniques. In this study it is suggested that in addition to present techniques the b wave to a wave relationship may be a useful index for evaluating the ERG. The ERG responses evoked by relatively bright flashes are recorded in the dark-adapted state. A plot of the b wave amplitude as a function of the a wave amplitude describes the functional integrity of the retina. A normally functioning retina should elicit an ERG response that fits the normal curve regardless of the apparatus used for ERG recording. The only constraint is the use of full-field illumination. This method is based on physiological considerations regarding the origin of the ERG components. Such a method will facilitate data exchange between centres and can also be used for clinical assessment of the retina.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (833K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Berson EL. Retinitis pigmentosa and allied diseases: applications of electroretinographic testing. Int Ophthalmol. 1981 Aug;4(1-2):7–22. [PubMed]
  • CONE RA. QUANTUM RELATIONS OF THE RAT ELECTRORETINOGRAM. J Gen Physiol. 1963 Jul;46:1267–1286. [PMC free article] [PubMed]
  • CONE RA. THE RAT ELECTRORETINOGRAM. I. CONTRASTING EFFECTS OF ADAPTATION ON THE AMPLITUDE AND LATENCY OF THE B-WAVE. J Gen Physiol. 1964 Jul;47:1089–1105. [PMC free article] [PubMed]
  • JOHNSON EP. The character of the B-wave in the human electroretinogram. AMA Arch Ophthalmol. 1958 Oct;60(4 Pt 1):565–591. [PubMed]
  • Berson EL, Gouras P, Hoff M. Temporal aspects of the electroretinogram. Arch Ophthalmol. 1969 Feb;81(2):207–214. [PubMed]
  • Brown KT. The eclectroretinogram: its components and their origins. Vision Res. 1968 Jun;8(6):633–677. [PubMed]
  • Rodieck RW. Components of the electroretinogram--a reappraisal. Vision Res. 1972 May;12(5):773–780. [PubMed]
  • BROWN KT, WIESEL TN. Localization of origins of electroretinogram components by intraretinal recording in the intact cat eye. J Physiol. 1961 Sep;158:257–280. [PubMed]
  • Miller RF, Dowling JE. Intracellular responses of the Müller (glial) cells of mudpuppy retina: their relation to b-wave of the electroretinogram. J Neurophysiol. 1970 May;33(3):323–341. [PubMed]
  • Kline RP, Ripps H, Dowling JE. Generation of b-wave currents in the skate retina. Proc Natl Acad Sci U S A. 1978 Nov;75(11):5727–5731. [PubMed]
  • Karowski CJ, Proenza LM. Relationship between Müller cell responses, a local transretinal potential, and potassium flux. J Neurophysiol. 1977 Mar;40(2):244–259. [PubMed]
  • Szamier RB, Ripps H, Chappell RL. Changes in ERG b-wave and Müller cell structure induced by alpha-aminoadipic acid. Neurosci Lett. 1981 Feb 6;21(3):307–312. [PubMed]
  • Green DG, Dowling JE, Siegel IM, Ripps H. Retinal mechanisms of visual adaptation in the skate. J Gen Physiol. 1975 Apr;65(4):483–502. [PMC free article] [PubMed]
  • Berson EL, Rosen JB, Simonoff EA. Electroretinographic testing as an aid in detection of carriers of X-chromosome-linked retinitis pigmentosa. Am J Ophthalmol. 1979 Apr;87(4):460–468. [PubMed]
  • van Lith G. Quantitative evaluation of the electroretinogram. Ophthalmologica. 1981;182(4):218–223. [PubMed]
  • Weleber RG. The effect of age on human cone and rod ganzfeld electroretinograms. Invest Ophthalmol Vis Sci. 1981 Mar;20(3):392–399. [PubMed]
  • Carr RE, Ripps H, Siegel IM, Weale RA. Rhodopsin and the electrical activity of the retina in congenital night blindness. Invest Ophthalmol. 1966 Oct;5(5):497–507. [PubMed]

Articles from The British Journal of Ophthalmology are provided here courtesy of BMJ Group