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Br J Ophthalmol. 1980 February; 64(2): 127–134.
PMCID: PMC1039363

A patterned macular dystrophy with yellow plaques and atrophic changes.


Three middle-aged male patients are described with a peculiar patterned dystrophy of the macula. The basic lesions are discrete yellow plaques typically confined to the macular area and radiating from the fovea. They appear to be located at the level of the retinal pigment epithelium (RPE). With the passage of time some of the yellow plaques altered in extent and configuration, and atrophic changes appeared or extended. Visual acuity and electrophysiological tests are either normal or only moderately affected. The lesions appear to be distinct from the patterned dystrophies of the retina already described and from other conditions characterised by yellow or white deposits at the level of the RPE.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • SJOGREN H. Dystrophia reticularis laminae pigmentosae retinae, an earlier not described hereditary eye disease. Acta Ophthalmol (Copenh) 1950;28(3):279–295. [PubMed]
  • Deutman AF, Rümke AM. Reticular dystrophy of the retinal pigment epithelium. Dystrophia reticularis laminae pigmentosa retinae of H. Sjogren. Arch Ophthalmol. 1969 Jul;82(1):4–9. [PubMed]
  • Deutman AF, van Blommestein JD, Henkes HE, Waardenburg PJ, Solleveld-van Driest E. Butterfly-shaped pigment dystrophy of the fovea. Arch Ophthalmol. 1970 May;83(5):558–569. [PubMed]
  • Hsieh RC, Fine BS, Lyons JS. Patterned dystrophies of the retinal pigment epithelium. Arch Ophthalmol. 1977 Mar;95(3):429–435. [PubMed]
  • Rabin AR, Berson EL. A full-field system for clinical electroretinography. Arch Ophthalmol. 1974 Jul;92(1):59–63. [PubMed]
  • Gass JD. A clinicopathologic study of a peculiar foveomacular dystrophy. Trans Am Ophthalmol Soc. 1974;72:139–156. [PMC free article] [PubMed]
  • Singerman LJ, Berkow JW, Patz A. Dominant slowly progressive macular dystrophy. Am J Ophthalmol. 1977 May;83(5):680–693. [PubMed]

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