PMCCPMCCPMCC

Search tips
Search criteria 

Advanced

 
Logo of jmedgeneJournal of Medical GeneticsVisit this articleSubmit a manuscriptReceive email alertsContact usBMJ
 
J Med Genet. 1993 June; 30(6): 460–464.
PMCID: PMC1016416

Complications of the naevoid basal cell carcinoma syndrome: results of a population based study.

Abstract

There are many potential complications which have been reported in association with the naevoid basal cell carcinoma syndrome. We have been able to show the relative frequencies of these problems in a population based study of 84 cases in the north west of England. The major complications of basal cell carcinomas and jaw cysts occur in over 90% of patients by 40 years of age, but may both occur before 10 years of age. Less well described complications are ovarian calcification or fibroma (24%), medulloblastoma (5%), cardiac fibroma (3%), cleft palate (5%), and ophthalmic abnormalities such as squint or cataract (26%). This study more clearly defines the possible complications of the syndrome and gives clearer guidelines for counselling and screening affected and at risk persons.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (924K), or click on a page image below to browse page by page.

Images in this article

Click on the image to see a larger version.

Articles from Journal of Medical Genetics are provided here courtesy of BMJ Group