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Br J Ind Med. 1975 August; 32(3): 239–243.
PMCID: PMC1008066

An evaluation of effect of airborne dust from a cotton mill on the guinea-pig ileum with reference to byssinosis.

Abstract

The effect of airborne dust on the guinea-pig ileum was studied. Tyrode extracts of airborne dust collected freshly in the cardroom of a cotton mill, and extracts of air pollutant samples drawn on the roof of the mill and of the local town hall were all found to induce the guinea-pig ileum to contract when applied in a tissue-bath. However, the force of contraction with air pollutants was rather greater than that with the cardroom dust. Considering the variables involved, the ileum response to the cardroom dust may have been due to ordinary air pollutants which constitute a significant part of the dust. It is concluded that this pharmacological phenomenon is probably not relevant in the context of byssinosis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Berry G, McKerrow CB, Molyneux MK, Rossiter CE, Tombleson JB. A study of the acute and chronic changes in ventilatory capacity of workers in Lancashire cotton mills. Br J Ind Med. 1973 Jan;30(1):25–36. [PMC free article] [PubMed]
  • DAVENPORT A, PATON WD. The pharmacological activity of extracts of cotton dust. Br J Ind Med. 1962 Jan;19:19–32. [PMC free article] [PubMed]
  • GADDUM JH. The technique of superfusion. Br J Pharmacol Chemother. 1953 Sep;8(3):321–326. [PubMed]

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