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West J Med. Aug 1990; 153(2): 160–167.
PMCID: PMC1002502
Selenium. Nutritional, toxicologic, and clinical aspects.
A. M. Fan and K. W. Kizer
Pesticide, Food, and Water Toxicology Unit, California Department of Health Services, Berkeley 94704.
Abstract
Despite the recent findings of environmental contamination, selenium toxicosis in humans is exceedingly rare in the United States, with the few known cases resulting from industrial accidents and an episode involving the ingestion of superpotent selenium supplements. Chronic selenosis is essentially unheard of in this country because of the typical diversity of the American diet. Nonetheless, because of the growing public interest in selenium as a dietary supplement and the occurrence of environmental selenium contamination, medical practitioners should be familiar with the nutritional, toxicologic, and clinical aspects of this trace element.
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