Search tips
Search criteria 


Logo of annrheumdAnnals of the Rheumatic DiseasesVisit this articleSubmit a manuscriptReceive email alertsContact usBMJ
Ann Rheum Dis. 1983 October; 42(5): 516–518.
PMCID: PMC1001286

Arthritis and angioimmunoblastic lymphadenopathy.


We report 2 contrasting cases of a seronegative polyarthritis associated with angioimmunoblastic lymphadenopathy (AILD). Both cases were nonerosive, with symmetrical involvement of the elbows, wrists, knees, and ankles. In one the arthritis appeared concurrently with the main systemic manifestations of AILD. The second presented with polyarthritis 18 months before the onset of AILD. This patient received azathioprine for 11 months before developing AILD, which raises the possibility of this drug being the causative agent.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (880K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Images in this article

Click on the image to see a larger version.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Michelis MF, Murdaugh HV. Selective hypoaldosteronism. An editorial revisited after 15 years. Am J Med. 1975 Jul;59(1):1–5. [PubMed]
  • Lukes RJ, Tindle BH. Immunoblastic lymphadenopathy. A hyperimmune entity resembling Hodgkin's disease. N Engl J Med. 1975 Jan 2;292(1):1–8. [PubMed]
  • Radaszkiewicz T, Lennert K. Lymphogranulomatosis X. Klinisches Bild, Therapie und Prognose. Dtsch Med Wochenschr. 1975 May 23;100(21):1157–1163. [PubMed]
  • Bensa J, Faure J, Martin H, Sotto J, Schaerer R. Letter: Levamisole in angio-immunoblastic lymphadenopathy. Lancet. 1976 May 15;1(7968):1081–1081. [PubMed]
  • Flandrin G. Adénopathies angio-immunoblastiques avec anémie auto-immune et hyperimmunoglobulinémie polyclonale. Nouv Presse Med. 1976 Jun 12;5(24):1521–1524. [PubMed]
  • Goudsmit R, Van Heerde P, Jöbsis AC, Borne AE, Somers R. (Angio) immunoblastic lymphadenopathy. A presentation of 5 cases. Neth J Med. 1976;19(4-5):171–184. [PubMed]
  • Pruzanski W, Sutton DM, Pantalony D. Angioimmunoblastic lymphadenopathy: an immunochemical study. Clin Immunol Immunopathol. 1976 Jul;6(1):62–76. [PubMed]
  • Rochant H, Reyes F, Vernant JP, Brun B, Schaeffer A, Sultan C, Tulliez M, Lebezu M, Dreyfus B. Aspects évolutifs de la lymphadénopathie angio-immunoblastique. A propos de trois observations. Ann Med Interne (Paris) 1976 Nov;127(11):857–861. [PubMed]
  • Rudders RA, DeLellis R. Immunoblastic lymphadenopathy. A mixed proliferation of T and B lymphocytes. Am J Clin Pathol. 1977 Oct;68(4):518–521. [PubMed]
  • Dujardin P, Audoly P, Cassuto JP, Kermarec J. Les lymphadénopathies angio-immunoblastiques avec dysprotéinémie. A propos de 5 observations. Sem Hop. 1977 Jun 23;53(24):1425–1429. [PubMed]
  • Cullen MH, Stansfeld AG, Oliver RT, Lister TA, Malpas JS. Angio-immunoblastic lymphadenopathy: report of ten cases and review of the literature. Q J Med. 1979 Jan;48(189):151–177. [PubMed]
  • Rothwell RS, Mant MJ, Davis P. Angioimmunoblastic lymphadenopathy associated with polyarthritis. Ann Rheum Dis. 1980 Aug;39(4):406–409. [PMC free article] [PubMed]
  • Bernengo MG, Levi L, Zina G. Skin lesions in angioimmunoblastic lymphadenopathy: histological and immunological studies. Br J Dermatol. 1981 Feb;104(2):131–139. [PubMed]

Articles from Annals of the Rheumatic Diseases are provided here courtesy of BMJ Group