Develop preliminary evidence-based criteria and guidelines for common geriatric syndromes through professional organizations
Regularly update criteria and guidelines over time
Apply criteria and guidelines in clinical practice across disciplines to improve recognition, diagnosis, and management of common geriatric syndromes
Local demonstration projects for implementation of clinical guidelines and programs to manage common geriatric syndromes
Test broader pleiotropic effects of agents (e.g. hormones, statins, antioxidants) or behavioral modifications (e.g. exercise, improved nutrition and weight loss) on relevant outcomes
Explore mechanisms by which such interventions exert effects which are beneficial in specific geriatric syndromes.
Develop and test unified intervention strategies (based on shared risk factors) across geriatric syndromes, and determine the impact of these strategies on long-term outcomes
Improve the basic pathophysiologic understanding of common geriatric syndromes through elucidation of complex mechanistic models which account for multiple pathways and potential synergisms between pathways
Design more targeted, more effective, and safer therapeutic strategies based on these new mechanistic models.
Enhance the translation of research into practice at institutional, local, and national levels
Work to develop national mandates to overcome barriers to translation, including development of clinical guidelines, quality improvement initiatives, Medicare reimbursement strategies, etc.