- Develop preliminary evidence-based criteria and guidelines for common geriatric syndromes through professional organizations
- Regularly update criteria and guidelines over time
- Apply criteria and guidelines in clinical practice across disciplines to improve recognition, diagnosis, and management of common geriatric syndromes
- Local demonstration projects for implementation of clinical guidelines and programs to manage common geriatric syndromes
- Test broader pleiotropic effects of agents (e.g. hormones, statins, antioxidants) or behavioral modifications (e.g. exercise, improved nutrition and weight loss) on relevant outcomes
- Explore mechanisms by which such interventions exert effects which are beneficial in specific geriatric syndromes.
- Develop and test unified intervention strategies (based on shared risk factors) across geriatric syndromes, and determine the impact of these strategies on long-term outcomes
- Improve the basic pathophysiologic understanding of common geriatric syndromes through elucidation of complex mechanistic models which account for multiple pathways and potential synergisms between pathways
- Design more targeted, more effective, and safer therapeutic strategies based on these new mechanistic models.
- Enhance the translation of research into practice at institutional, local, and national levels
- Work to develop national mandates to overcome barriers to translation, including development of clinical guidelines, quality improvement initiatives, Medicare reimbursement strategies, etc.